Caenorhabditis elegans      (pS/pT)/PBD


※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512


There are 3 genes.  Reviewed (3 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cae-0804
WBGene00004042
P34331
plk-1; plc1; C14B9.4
2
iEKPD-Cae-0805
WBGene00004043
Q9N2L7
plk-2; Y71F9B.7
3
iEKPD-Cae-0806
WBGene00004044
Q20845
plk-3; plc2; F55G1.8