Canis familiaris      (pS/pT)/PBD


※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Caf-1284
ENSCAFG00000017658.4
J9P0Q4
PLK1
2
iEKPD-Caf-1261
ENSCAFG00000006975.4
E2RGZ7
PLK2
3
iEKPD-Caf-1258
ENSCAFG00000004713.4
E2RGK9
PLK3