Carlito syrichta      (pS/pT)/PBD


※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cas-1187
ENSTSYG00000001333.2
A0A1U7TBJ7
PLK1
2
iEKPD-Cas-1199
ENSTSYG00000006936.2
A0A1U7SZ67
PLK2
3
iEKPD-Cas-1212
ENSTSYG00000025938.1
A0A1U7UAU1
PLK3
4
iEKPD-Cas-1226
ENSTSYG00000037479.1
A0A1U7SGH8
PLK5