Danio rerio      (pS/pT)/PBD


※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-2005
ENSDARG00000058471.4
Q6DRK7
plk1
2
iEKPD-Dar-2021
ENSDARG00000090752.3
E7EXD4
plk2a
3
iEKPD-Dar-1993
ENSDARG00000019130.7
A8WHV5
plk2b
4
iEKPD-Dar-2002
ENSDARG00000038754.6
B0S6K2
plk3; DKEY-4I23.3-001