Latimeria chalumnae      (pS/pT)/PBD


※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Lac-1248
ENSLACG00000004574.1
H3A675
2
iEKPD-Lac-1247
ENSLACG00000004130.2
H3A4R9
PLK1
3
iEKPD-Lac-1262
ENSLACG00000010400.1
H3AQ93
PLK2
4
iEKPD-Lac-1244
ENSLACG00000003507.1
H3A2R9
PLK3