Sarcophilus harrisii      (pS/pT)/PBD


※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sah-1165
ENSSHAG00000005264.1
G3VS91
2
iEKPD-Sah-1176
ENSSHAG00000011352.1
G3WCX3
3
iEKPD-Sah-1181
ENSSHAG00000012474.1
G3WGQ6
4
iEKPD-Sah-1187
ENSSHAG00000015439.1
G3WRY1
PLK2