※ PBD family introduction

    C-terminal Polo-box domains (PBDs) of Plks, acting as pS/pT-binding modules, are crucial for orchestrating the proper sub-cellular localizations and kinase activities of Plks during multiple stages of mitosis. Moreover, Plk-mediated phosphoregulation can regulate a variety of biological and cellular processes beyond mitosis, such as DNA damage, centriole duplication, transcription regulation and stress-activated MAPK cascade (1).

Reference
1. Liu, Z. (2013) Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes . Brief Bioinform, 14, 344-60. PMID: 22851512

  Reviewed (0)  or Unreviewed (3) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-1287	ENSTGUG00000006112.1	H0Z6U1	PLK1
2		iEKPD-Tag-1280	ENSTGUG00000002609.1	H0YWM2	PLK2
3		iEKPD-Tag-1291	ENSTGUG00000007715.1	H0ZBK6	PLK3