※ PDZ family introduction

    The PDZ domain is a common structural domain of 80-90 amino-acids found in the signaling proteins of bacteria, yeast, plants, viruses and animals. Proteins containing PDZ domains play a key role in anchoring receptor proteins in the membrane to cytoskeletal components. Proteins with these domains help hold together and organize signaling complexes at cellular membranes. These domains play a key role in the formation and function of signal transduction complexes. The PDZ domain of RGS3 were found to bind to the Tyr304 phosphopeptide of ephrin B2 in recent study (1).

Reference
1. Su, Z. (2011) Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein. Eur J Biochem, 271, 1725-36. PMID: 15096211

  Reviewed (1)  or Unreviewed (112) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mim-0843	ENSMICG00000013929.3	Q2QL92	TES
2		iEKPD-Mim-0754	ENSMICG00000010194.3
3		iEKPD-Mim-0755	ENSMICG00000014246.3
4		iEKPD-Mim-0756	ENSMICG00000017070.3
5		iEKPD-Mim-0757	ENSMICG00000002258.3
6		iEKPD-Mim-1306	ENSMICG00000043519.1
7		iEKPD-Mim-1307	ENSMICG00000042078.1
8		iEKPD-Mim-1305	ENSMICG00000012207.3
9		iEKPD-Mim-1308	ENSMICG00000009535.3
10		iEKPD-Mim-0758	ENSMICG00000038001.2
11		iEKPD-Mim-0759	ENSMICG00000006875.3
12		iEKPD-Mim-0760	ENSMICG00000004948.3
13		iEKPD-Mim-0761	ENSMICG00000016873.3
14		iEKPD-Mim-0762	ENSMICG00000012615.3
15		iEKPD-Mim-1304	ENSMICG00000004288.3
16		iEKPD-Mim-0763	ENSMICG00000044252.1
17		iEKPD-Mim-0764	ENSMICG00000002755.3
18		iEKPD-Mim-0765	ENSMICG00000015359.3
19		iEKPD-Mim-0766	ENSMICG00000002908.3
20		iEKPD-Mim-0767	ENSMICG00000014731.3
21		iEKPD-Mim-1291	ENSMICG00000035687.2
22		iEKPD-Mim-0768	ENSMICG00000005916.3
23		iEKPD-Mim-0769	ENSMICG00000000017.3
24		iEKPD-Mim-0770	ENSMICG00000036133.2
25		iEKPD-Mim-0771	ENSMICG00000009022.3
26		iEKPD-Mim-0772	ENSMICG00000003968.3
27		iEKPD-Mim-0773	ENSMICG00000005547.3
28		iEKPD-Mim-0775	ENSMICG00000008515.3
29		iEKPD-Mim-0776	ENSMICG00000015931.3
30		iEKPD-Mim-0777	ENSMICG00000009358.3
31		iEKPD-Mim-0778	ENSMICG00000033517.2
32		iEKPD-Mim-0779	ENSMICG00000032240.2
33		iEKPD-Mim-0780	ENSMICG00000014370.3
34		iEKPD-Mim-0781	ENSMICG00000004936.3
35		iEKPD-Mim-0782	ENSMICG00000028041.2
36		iEKPD-Mim-0783	ENSMICG00000005165.3
37		iEKPD-Mim-0784	ENSMICG00000015544.3
38		iEKPD-Mim-0785	ENSMICG00000033894.2
39		iEKPD-Mim-0786	ENSMICG00000001818.3
40		iEKPD-Mim-1309	ENSMICG00000009602.3
41		iEKPD-Mim-0787	ENSMICG00000046201.1
42		iEKPD-Mim-0788	ENSMICG00000007584.3
43		iEKPD-Mim-0789	ENSMICG00000046407.1
44		iEKPD-Mim-0790	ENSMICG00000037737.2
45		iEKPD-Mim-0791	ENSMICG00000014239.3
46		iEKPD-Mim-0792	ENSMICG00000032757.2
47		iEKPD-Mim-0793	ENSMICG00000003571.3
48		iEKPD-Mim-0794	ENSMICG00000043485.1
49		iEKPD-Mim-0795	ENSMICG00000005504.3
50		iEKPD-Mim-1310	ENSMICG00000006447.3
51		iEKPD-Mim-0796	ENSMICG00000015130.3
52		iEKPD-Mim-0797	ENSMICG00000028272.2
53		iEKPD-Mim-0798	ENSMICG00000034377.2
54		iEKPD-Mim-0799	ENSMICG00000033074.2
55		iEKPD-Mim-1311	ENSMICG00000014756.3
56		iEKPD-Mim-0800	ENSMICG00000027183.2
57		iEKPD-Mim-0801	ENSMICG00000027692.2
58		iEKPD-Mim-0802	ENSMICG00000011152.3
59		iEKPD-Mim-0803	ENSMICG00000016807.3
60		iEKPD-Mim-0804	ENSMICG00000028737.2
61		iEKPD-Mim-0805	ENSMICG00000029035.2
62		iEKPD-Mim-0806	ENSMICG00000029530.2
63		iEKPD-Mim-0807	ENSMICG00000012516.3
64		iEKPD-Mim-0808	ENSMICG00000026651.2
65		iEKPD-Mim-0809	ENSMICG00000027040.2
66		iEKPD-Mim-1285	ENSMICG00000002104.3
67		iEKPD-Mim-0810	ENSMICG00000009042.3
68		iEKPD-Mim-0811	ENSMICG00000000638.3
69		iEKPD-Mim-1312	ENSMICG00000007623.3
70		iEKPD-Mim-0812	ENSMICG00000011120.3
71		iEKPD-Mim-0813	ENSMICG00000000927.3
72		iEKPD-Mim-0814	ENSMICG00000008147.3
73		iEKPD-Mim-0815	ENSMICG00000015914.3
74		iEKPD-Mim-1293	ENSMICG00000046058.1
75		iEKPD-Mim-0816	ENSMICG00000006389.3
76		iEKPD-Mim-0817	ENSMICG00000004315.3
77		iEKPD-Mim-0818	ENSMICG00000035602.2
78		iEKPD-Mim-0819	ENSMICG00000012185.3
79		iEKPD-Mim-0820	ENSMICG00000014215.3
80		iEKPD-Mim-0821	ENSMICG00000002125.3
81		iEKPD-Mim-0822	ENSMICG00000010772.3
82		iEKPD-Mim-0823	ENSMICG00000005609.3
83		iEKPD-Mim-0824	ENSMICG00000003919.3
84		iEKPD-Mim-0825	ENSMICG00000029638.2
85		iEKPD-Mim-0826	ENSMICG00000032222.2
86		iEKPD-Mim-1296	ENSMICG00000008520.3
87		iEKPD-Mim-0827	ENSMICG00000009429.3
88		iEKPD-Mim-0828	ENSMICG00000013369.3
89		iEKPD-Mim-0829	ENSMICG00000032853.2
90		iEKPD-Mim-0830	ENSMICG00000011010.3
91		iEKPD-Mim-0831	ENSMICG00000010914.3
92		iEKPD-Mim-0832	ENSMICG00000011267.3
93		iEKPD-Mim-1261	ENSMICG00000011481.3
94		iEKPD-Mim-1246	ENSMICG00000001029.3
95		iEKPD-Mim-1272	ENSMICG00000016221.3
96		iEKPD-Mim-0833	ENSMICG00000014417.3
97		iEKPD-Mim-0834	ENSMICG00000001903.3
98		iEKPD-Mim-1278	ENSMICG00000034292.2
99		iEKPD-Mim-1295	ENSMICG00000015809.3
100		iEKPD-Mim-0835	ENSMICG00000015034.3
101		iEKPD-Mim-0836	ENSMICG00000029739.2
102		iEKPD-Mim-0837	ENSMICG00000012163.3
103		iEKPD-Mim-1245	ENSMICG00000000276.3
104		iEKPD-Mim-0838	ENSMICG00000042175.1
105		iEKPD-Mim-0839	ENSMICG00000002912.3
106		iEKPD-Mim-0840	ENSMICG00000042337.1
107		iEKPD-Mim-0841	ENSMICG00000002828.3
108		iEKPD-Mim-0842	ENSMICG00000012960.3
109		iEKPD-Mim-1313	ENSMICG00000005231.3
110		iEKPD-Mim-0844	ENSMICG00000013790.3
111		iEKPD-Mim-1297	ENSMICG00000037166.2
112		iEKPD-Mim-0845	ENSMICG00000002819.3
113		iEKPD-Mim-0774	ENSMICG00000008163.3	F5A683	TRIM5