※ PDZ family introduction

    The PDZ domain is a common structural domain of 80-90 amino-acids found in the signaling proteins of bacteria, yeast, plants, viruses and animals. Proteins containing PDZ domains play a key role in anchoring receptor proteins in the membrane to cytoskeletal components. Proteins with these domains help hold together and organize signaling complexes at cellular membranes. These domains play a key role in the formation and function of signal transduction complexes. The PDZ domain of RGS3 were found to bind to the Tyr304 phosphopeptide of ephrin B2 in recent study (1).

Reference
1. Su, Z. (2011) Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein. Eur J Biochem, 271, 1725-36. PMID: 15096211

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ora-0732	ENSOANG00000005925.2	F6PRF5
2		iEKPD-Ora-1191	ENSOANG00000015075.2	F6PQQ3
3		iEKPD-Ora-0733	ENSOANG00000013213.2	F6Z8V4
4		iEKPD-Ora-0736	ENSOANG00000009734.2	F6ZTZ8
5		iEKPD-Ora-0739	ENSOANG00000006832.3	F6RJQ3
6		iEKPD-Ora-0741	ENSOANG00000030734.1	K7EE65
7		iEKPD-Ora-0745	ENSOANG00000007679.2	F6W7S7
8		iEKPD-Ora-0746	ENSOANG00000011280.2	F7DFZ2
9		iEKPD-Ora-0747	ENSOANG00000002130.3	F6TQK2
10		iEKPD-Ora-1190	ENSOANG00000006964.3	F7E236
11		iEKPD-Ora-0748	ENSOANG00000000746.1	F6YKZ4
12		iEKPD-Ora-0749	ENSOANG00000021618.2	F6SSQ3
13		iEKPD-Ora-0750	ENSOANG00000021471.2	F6SUR3
14		iEKPD-Ora-0752	ENSOANG00000022369.2	F6SFU0
15		iEKPD-Ora-0756	ENSOANG00000002819.1	F6ZJF5
16		iEKPD-Ora-0760	ENSOANG00000003691.3	F7DY98
17		iEKPD-Ora-0762	ENSOANG00000001345.1	F7F2S8
18		iEKPD-Ora-0763	ENSOANG00000031110.1	K7EE74
19		iEKPD-Ora-0766	ENSOANG00000013287.2	F6S5G0
20		iEKPD-Ora-0770	ENSOANG00000011205.2	F7FJB4
21		iEKPD-Ora-0771	ENSOANG00000008414.3	F6VVC9
22		iEKPD-Ora-0773	ENSOANG00000020215.2	F7BN17
23		iEKPD-Ora-0775	ENSOANG00000032112.1	K7EBL5
24		iEKPD-Ora-0777	ENSOANG00000029732.1	K7EED2
25		iEKPD-Ora-0781	ENSOANG00000029101.1	K7EFZ7
26		iEKPD-Ora-0782	ENSOANG00000028460.1	K7E6Q5
27		iEKPD-Ora-0783	ENSOANG00000002974.2	F6V3W2
28		iEKPD-Ora-0785	ENSOANG00000003311.3	F7AF95
29		iEKPD-Ora-0787	ENSOANG00000031703.1	K7EDR2
30		iEKPD-Ora-0788	ENSOANG00000004480.4	F7DEM7
31		iEKPD-Ora-0793	ENSOANG00000006022.3	F6V5R4
32		iEKPD-Ora-0795	ENSOANG00000001502.2	F7DCC4
33		iEKPD-Ora-1155	ENSOANG00000005570.3	F6PZ10
34		iEKPD-Ora-1181	ENSOANG00000012067.3	F7FW16
35		iEKPD-Ora-0800	ENSOANG00000000889.2	F6WPV1
36		iEKPD-Ora-0801	ENSOANG00000013258.3	F6TWL4
37		iEKPD-Ora-0802	ENSOANG00000009673.2	F6SVY1
38		iEKPD-Ora-0803	ENSOANG00000005458.2	F7C2F6
39		iEKPD-Ora-1161	ENSOANG00000009787.4	F6TNQ9
40		iEKPD-Ora-0804	ENSOANG00000009480.4	F7G0X8
41		iEKPD-Ora-0805	ENSOANG00000029224.1	K7E9G8
42		iEKPD-Ora-1167	ENSOANG00000011267.3	F7DPD5
43		iEKPD-Ora-0806	ENSOANG00000008233.1	F7BT31
44		iEKPD-Ora-0807	ENSOANG00000001726.2	F7F018
45		iEKPD-Ora-0809	ENSOANG00000029398.1	K7E8K4
46		iEKPD-Ora-0810	ENSOANG00000014617.2	F7EHC2
47		iEKPD-Ora-0812	ENSOANG00000030184.1	K7E8C3
48		iEKPD-Ora-0813	ENSOANG00000003152.3	F6SD69
49		iEKPD-Ora-0814	ENSOANG00000012460.1	F7FUG7
50		iEKPD-Ora-0759	ENSOANG00000005867.3	F6WXV0	AFDN
51		iEKPD-Ora-1195	ENSOANG00000002093.2	F6UN75	APBA1
52		iEKPD-Ora-1193	ENSOANG00000006293.3	F6US59	APBA3
53		iEKPD-Ora-0778	ENSOANG00000006268.2	F6VQH8	ARHGEF12
54		iEKPD-Ora-0808	ENSOANG00000010656.3	F6XS37	CNKSR2
55		iEKPD-Ora-0774	ENSOANG00000006129.2	F6WTB7	CYTIP
56		iEKPD-Ora-1189	ENSOANG00000008737.3	F6Z626	DLG1
57		iEKPD-Ora-0784	ENSOANG00000008082.3	F7G9D8	DVL3
58		iEKPD-Ora-0757	ENSOANG00000005023.3	F7FZ26	ERBIN
59		iEKPD-Ora-1194	ENSOANG00000002619.3	F7E094	FRMPD4
60		iEKPD-Ora-0740	ENSOANG00000013266.3	F6T1M4	FXN
61		iEKPD-Ora-0754	ENSOANG00000028575.1	K7E8L1	LIN7A
62		iEKPD-Ora-0751	ENSOANG00000009721.3	F7AL97	LIN7C
63		iEKPD-Ora-0735	ENSOANG00000009060.3	F7D1I1	LNX2
64		iEKPD-Ora-0811	ENSOANG00000029177.1	K7EGR7	LOC100074491
65		iEKPD-Ora-0776	ENSOANG00000008591.2	F7CBM3	LOC100077772
66		iEKPD-Ora-0734	ENSOANG00000006229.2	F6VW92	LOC100082539
67		iEKPD-Ora-0758	ENSOANG00000029247.1	K7E7G9	LOC100088170
68		iEKPD-Ora-0794	ENSOANG00000002963.2	F6ZHC5	LOC103165502
69		iEKPD-Ora-0769	ENSOANG00000028247.1	K7EBZ5	LOC103165640
70		iEKPD-Ora-0765	ENSOANG00000031447.1	K7E7U7	LOC103167666
71		iEKPD-Ora-0768	ENSOANG00000021346.2	F6S0Y7	MAGI1
72		iEKPD-Ora-1192	ENSOANG00000002645.3	F7B6N8	MAGI3
73		iEKPD-Ora-1144	ENSOANG00000001293.3	F7FX51	MAST3
74		iEKPD-Ora-0731	ENSOANG00000013531.3	F7DX83	MPDZ
75		iEKPD-Ora-0799	ENSOANG00000008715.2	F7CAB5	MPP1
76		iEKPD-Ora-0792	ENSOANG00000005411.2	F6Q1K1	MPP5
77		iEKPD-Ora-0789	ENSOANG00000006040.3	F6QL81	MPP7
78		iEKPD-Ora-0737	ENSOANG00000006064.4	F7CI76	PARD3
79		iEKPD-Ora-0742	ENSOANG00000014041.3	F6Q8U5	PARD3B
80		iEKPD-Ora-0796	ENSOANG00000008676.2	F6QBS4	PARD6B
81		iEKPD-Ora-0738	ENSOANG00000012216.2	F7FP93	PDZD3
82		iEKPD-Ora-1152	ENSOANG00000005181.3	F6Q5R3	PDZD4
83		iEKPD-Ora-0743	ENSOANG00000007308.1	F6XVJ6	PDZD7
84		iEKPD-Ora-0767	ENSOANG00000003429.2	F7DHL4	PDZRN4
85		iEKPD-Ora-0761	ENSOANG00000014682.2	F7CXB0	PICK1
86		iEKPD-Ora-0786	ENSOANG00000000561.4	F7G3M1	PREX1
87		iEKPD-Ora-0780	ENSOANG00000013504.3	F7E6B0	PREX2
88		iEKPD-Ora-1179	ENSOANG00000014464.2	F7BD43	PTPN3
89		iEKPD-Ora-0798	ENSOANG00000014970.2	F7BXG1	RAPGEF2
90		iEKPD-Ora-0791	ENSOANG00000006961.3	F7E268	RAPGEF6
91		iEKPD-Ora-0779	ENSOANG00000003536.2	F7DQY0	RHPN1
92		iEKPD-Ora-0744	ENSOANG00000005034.3	F6Y5R8	SDCBP
93		iEKPD-Ora-0790	ENSOANG00000007407.2	F7CIH2	SHANK2
94		iEKPD-Ora-0755	ENSOANG00000007270.2	F7CKJ6	SNTG1
95		iEKPD-Ora-0753	ENSOANG00000009857.3	F6ZT92	SNTG2
96		iEKPD-Ora-0764	ENSOANG00000002669.2	F7ADQ9	SYNJ2BP
97		iEKPD-Ora-0797	ENSOANG00000003312.2	F7AEX7	SYNPO2
98		iEKPD-Ora-0772	ENSOANG00000012695.3	F7A7L7	TAX1BP3