※ PDZ family introduction

    The PDZ domain is a common structural domain of 80-90 amino-acids found in the signaling proteins of bacteria, yeast, plants, viruses and animals. Proteins containing PDZ domains play a key role in anchoring receptor proteins in the membrane to cytoskeletal components. Proteins with these domains help hold together and organize signaling complexes at cellular membranes. These domains play a key role in the formation and function of signal transduction complexes. The PDZ domain of RGS3 were found to bind to the Tyr304 phosphopeptide of ephrin B2 in recent study (1).

Reference
1. Su, Z. (2011) Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein. Eur J Biochem, 271, 1725-36. PMID: 15096211

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-0826	ENSTGUG00000009783.1	H0ZHM7
2		iEKPD-Tag-0832	ENSTGUG00000001901.1	H0YUJ2
3		iEKPD-Tag-0834	ENSTGUG00000002745.1	H0YX01
4		iEKPD-Tag-0835	ENSTGUG00000008085.1	H0ZCM1
5		iEKPD-Tag-0847	ENSTGUG00000007932.1	H0ZC60
6		iEKPD-Tag-0852	ENSTGUG00000009777.1	H0ZHM2
7		iEKPD-Tag-0853	ENSTGUG00000015845.1	H0ZZW1
8		iEKPD-Tag-0866	ENSTGUG00000002599.1	H0YWK4
9		iEKPD-Tag-0870	ENSTGUG00000014353.1	H0ZVS9
10		iEKPD-Tag-0878	ENSTGUG00000008541.1	H0ZDZ6
11		iEKPD-Tag-1310	ENSTGUG00000004680.1	H0Z2M4
12		iEKPD-Tag-0881	ENSTGUG00000010064.1	H0ZIG2
13		iEKPD-Tag-0884	ENSTGUG00000001310.1	H0YSU1
14		iEKPD-Tag-0887	ENSTGUG00000005701.1	H0Z5L0
15		iEKPD-Tag-0890	ENSTGUG00000005571.1	H0Z596
16		iEKPD-Tag-0896	ENSTGUG00000000949.1	H0YRR4
17		iEKPD-Tag-0901	ENSTGUG00000003500.1	H0YZ70
18		iEKPD-Tag-0905	ENSTGUG00000014896.1	H0ZXA2
19		iEKPD-Tag-0906	ENSTGUG00000015512.1	H0ZYZ2
20		iEKPD-Tag-0907	ENSTGUG00000017363.1	H1A426
21		iEKPD-Tag-0908	ENSTGUG00000016097.1	H1A0K5
22		iEKPD-Tag-0862	ENSTGUG00000009578.1	H0ZH64	AFDN
23		iEKPD-Tag-1330	ENSTGUG00000001066.1	H0YS41	APBA1
24		iEKPD-Tag-1331	ENSTGUG00000005613.1	H0Z5F2	APBA2
25		iEKPD-Tag-1329	ENSTGUG00000000142.1	H0YPE8	APBA3
26		iEKPD-Tag-0897	ENSTGUG00000001167.1	H0YSE2	ARHGAP21
27		iEKPD-Tag-0873	ENSTGUG00000000421.1	H0YQ85	ARHGEF12
28		iEKPD-Tag-1288	ENSTGUG00000006375.1	H0Z7P7	CASK
29		iEKPD-Tag-0902	ENSTGUG00000007450.1	H0ZAS6	CNKSR2
30		iEKPD-Tag-0874	ENSTGUG00000016854.1	H1A2N1	CYTIP
31		iEKPD-Tag-0833	ENSTGUG00000008892.1	H0ZF65	DLG1
32		iEKPD-Tag-1324	ENSTGUG00000012956.1	H0ZRV1	DLG2
33		iEKPD-Tag-0839	ENSTGUG00000007374.1	H0ZAP8	DLG3
34		iEKPD-Tag-0837	ENSTGUG00000006471.1	H0Z7Y5	DLG5
35		iEKPD-Tag-0880	ENSTGUG00000003140.1	H0YY89	DVL1
36		iEKPD-Tag-0882	ENSTGUG00000010112.1	H0ZIM0	DVL3
37		iEKPD-Tag-0858	ENSTGUG00000002890.1	H0YXJ3	ERBIN
38		iEKPD-Tag-1334	ENSTGUG00000008266.1	H0ZD69	FRMPD4
39		iEKPD-Tag-0903	ENSTGUG00000006817.1	H0Z8X0	GIPC2
40		iEKPD-Tag-0859	ENSTGUG00000011901.1	H0ZNT6	GOPC
41		iEKPD-Tag-0909	ENSTGUG00000000460.1	H0YQB3	GORASP1
42		iEKPD-Tag-0900	ENSTGUG00000008120.1	H0ZCS5	GORASP2
43		iEKPD-Tag-0823	ENSTGUG00000006648.1	H0Z8G7	GRIP1
44		iEKPD-Tag-0824	ENSTGUG00000008370.1	H0ZDI8	GRIP2
45		iEKPD-Tag-0849	ENSTGUG00000001898.1	H0YUI6	IL16
46		iEKPD-Tag-0851	ENSTGUG00000007913.1	H0ZC54	IL16
47		iEKPD-Tag-0856	ENSTGUG00000007757.1	H0ZBM6	LIN7A
48		iEKPD-Tag-0855	ENSTGUG00000004736.1	H0Z2T0	LIN7C
49		iEKPD-Tag-0831	ENSTGUG00000007807.1	H0ZBU8	LNX1
50		iEKPD-Tag-0830	ENSTGUG00000011590.1	H0ZMX9	LNX2
51		iEKPD-Tag-0829	ENSTGUG00000005722.1	H0Z5P7	LOC100230322
52		iEKPD-Tag-1327	ENSTGUG00000009560.1	H0ZH11	MAGI1
53		iEKPD-Tag-1328	ENSTGUG00000002672.1	H0YWU2	MAGI2
54		iEKPD-Tag-1326	ENSTGUG00000017520.1	H1A4I8	MAGI3
55		iEKPD-Tag-1293	ENSTGUG00000008089.1	H0ZCQ4	MAST2
56		iEKPD-Tag-1275	ENSTGUG00000000403.1	H0YQ64	MAST3
57		iEKPD-Tag-1281	ENSTGUG00000002955.1	H0YXP2	MAST4
58		iEKPD-Tag-0825	ENSTGUG00000004679.1	H0Z2M5	MPDZ
59		iEKPD-Tag-0886	ENSTGUG00000006812.1	H0Z901	MPP1
60		iEKPD-Tag-0892	ENSTGUG00000002948.1	H0YXM9	MPP3
61		iEKPD-Tag-0904	ENSTGUG00000010238.1	H0ZIZ4	MPP4
62		iEKPD-Tag-0889	ENSTGUG00000011569.1	H0ZMV4	MPP5
63		iEKPD-Tag-0883	ENSTGUG00000001078.1	H0YS60	MPP7
64		iEKPD-Tag-0885	ENSTGUG00000010372.1	H0ZJG3	NOS1
65		iEKPD-Tag-0844	ENSTGUG00000000932.1	H0YRQ8	PARD3
66		iEKPD-Tag-0845	ENSTGUG00000009770.1	H0ZHN4	PARD3B
67		iEKPD-Tag-0876	ENSTGUG00000005063.1	H0Z3R1	PARD6A
68		iEKPD-Tag-0893	ENSTGUG00000008670.1	H0ZEB2	PARD6B
69		iEKPD-Tag-0899	ENSTGUG00000008898.1	H0ZEZ6	PARD6G
70		iEKPD-Tag-0875	ENSTGUG00000007148.1	H0Z9V6	PDLIM1
71		iEKPD-Tag-0895	ENSTGUG00000006848.1	H0Z906	PDLIM3
72		iEKPD-Tag-0888	ENSTGUG00000001365.1	H0YSZ9	PDLIM4
73		iEKPD-Tag-0910	ENSTGUG00000000408.1	H0YQ65	PDLIM7
74		iEKPD-Tag-0863	ENSTGUG00000002616.1	H0YWL8	PDZD11
75		iEKPD-Tag-0841	ENSTGUG00000000372.1	H0YQ27	PDZD3
76		iEKPD-Tag-0846	ENSTGUG00000010061.1	H0ZIG0	PDZD7
77		iEKPD-Tag-0827	ENSTGUG00000013529.1	H0ZTI4	PDZK1
78		iEKPD-Tag-0864	ENSTGUG00000014523.1	H0ZWA9	PDZRN3
79		iEKPD-Tag-0848	ENSTGUG00000005793.1	H0Z5W4	PDZRN4
80		iEKPD-Tag-0861	ENSTGUG00000010456.1	H0ZJM3	PICK1
81		iEKPD-Tag-0869	ENSTGUG00000001566.1	H0YTL1	PPP1R9A
82		iEKPD-Tag-0898	ENSTGUG00000008911.1	H0ZF37	PREX1
83		iEKPD-Tag-0879	ENSTGUG00000011400.1	H0ZME3	PREX2
84		iEKPD-Tag-1313	ENSTGUG00000008110.1	H0ZCT3	PTPN3
85		iEKPD-Tag-0877	ENSTGUG00000007743.1	H0ZBM2	RADIL
86		iEKPD-Tag-0891	ENSTGUG00000005715.1	H0Z5S4	RAPGEF2
87		iEKPD-Tag-1332	ENSTGUG00000010365.1	H0ZJF0	RGS12
88		iEKPD-Tag-0871	ENSTGUG00000012739.1	H0ZR73	RHPN1
89		iEKPD-Tag-1318	ENSTGUG00000012695.1	H0ZR38	RIMS1
90		iEKPD-Tag-1317	ENSTGUG00000012161.1	H0ZPK5	RIMS2
91		iEKPD-Tag-1325	ENSTGUG00000012791.1	H0ZRD1	SCRIB
92		iEKPD-Tag-0850	ENSTGUG00000006915.1	H0Z967	SDCBP2
93		iEKPD-Tag-0843	ENSTGUG00000011134.1	H0ZLL3	SDCBP
94		iEKPD-Tag-0872	ENSTGUG00000008912.1	H0ZF08	SLC9A3R1
95		iEKPD-Tag-0860	ENSTGUG00000006561.1	H0Z841	SLC9A3R2
96		iEKPD-Tag-0868	ENSTGUG00000003805.1	H0Z028	SNTA1
97		iEKPD-Tag-0857	ENSTGUG00000010922.1	H0ZKZ8	SNTG1
98		iEKPD-Tag-0854	ENSTGUG00000012954.1	H0ZRV0	SNTG2
99		iEKPD-Tag-1333	ENSTGUG00000009465.1	H0ZGP5	STXBP4
100		iEKPD-Tag-0865	ENSTGUG00000011384.1	H0ZMA7	SYNJ2BP
101		iEKPD-Tag-0894	ENSTGUG00000007020.1	H0Z9H3	SYNPO2L
102		iEKPD-Tag-0867	ENSTGUG00000006910.1	H0Z959	TAX1BP3
103		iEKPD-Tag-0828	ENSTGUG00000005653.1	H0Z5K7	TJP1
104		iEKPD-Tag-0838	ENSTGUG00000004208.1	H0Z1C2	TJP2
105		iEKPD-Tag-0840	ENSTGUG00000000147.1	H0YPF7	TJP3
106		iEKPD-Tag-0842	ENSTGUG00000008748.1	H0ZEN3	USH1C
107		iEKPD-Tag-0836	ENSTGUG00000003170.1	H0YY97	WHRN