Neurospora crassa      (pS/pT)/WD40


※ WD40 family introduction

    WD-40 repeats (also known as WD or beta-transducin repeats) are short ~40 amino acid motifs, often terminating in a Trp-Asp (W-D) dipeptide. WD40 repeats usually assume a 7-8 bladed beta-propeller fold, but proteins have been found with 4 to 16 repeated units, which also form a circularised beta-propeller structure. WD-repeat proteins are a large family found in all eukaryotes and are implicated in a variety of functions ranging from signal transduction and transcription regulation to cell cycle control and apoptosis. Repeated WD40 motifs act as a site for protein-protein interaction, and proteins containing WD40 repeats are known to serve as platforms for the assembly of protein complexes or mediators of transient interplay among other proteins. A widespread protein-interaction domain, of which some members (bTRCP and CDC4) bind specifically to pSer or pThr motifs. Many or most are probably not phospho-specific (1).

Reference
1. http://www.ebi.ac.uk/interpro/entry/IPR001680


There are 93 genes.  Reviewed (19 or Unreviewed (74

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Nec-0274
NCU02466
Q7SG97
apg-14; hsv2; NCU02466
2
iEKPD-Nec-0267
NCU11283
A7UWE6
asa-1; NCU11283
3
iEKPD-Nec-0202
NCU03794
Q9C270
B18D24.40; NCU03794
4
iEKPD-Nec-0224
NCU05426
Q9P5P0
cia1; B8B20.360; NCU05426
5
iEKPD-Nec-0187
NCU05810
Q01369
cpc-2; NCU05810
6
iEKPD-Nec-0249
NCU03321
Q7SEM3
erb1; NCU03321
7
iEKPD-Nec-0212
NCU06679
Q7S7N3
hat-2; NCU06679
8
iEKPD-Nec-0215
NCU04035
Q7RZI0
hir-1; B10H18.120; NCU04035
9
iEKPD-Nec-0196
NCU07724
Q7S8R5
mdv1; NCU07724
10
iEKPD-Nec-0260
NCU09302
Q7S1H9
NCU09302; NCU11420
11
iEKPD-Nec-0193
NCU04534
Q7RY30
nmp-1; lis1-1; mtb4A; nudf-2; pac1-1; ro-15; NCU04534
12
iEKPD-Nec-0195
NCU04312
Q7S7L4
nmp-2; dyn-5; lis1-2; mtb4B; nudf-1; pac1-2; B7H23.150; NCU04312
13
iEKPD-Nec-0211
NCU04063
Q7RZF5
nup-20; sec13; NCU04063
14
iEKPD-Nec-0214
NCU00037
Q7RY68
paa-1; pfs2; NCU00037
15
iEKPD-Nec-0189
NCU06205
P78706
rco-1; NCU06205
16
iEKPD-Nec-0188
NCU08563
Q01277
scon-2; B13M15.090; NCU08563
17
iEKPD-Nec-0240
NCU06738
Q873A1
sec31; B24N11.230; NCU06738
18
iEKPD-Nec-0235
NCU03876
Q7RXH4
tif-34; NCU03876
19
iEKPD-Nec-0225
NCU03764
Q9C2I5
ytm1; 93G11.070; NCU03764
20
iEKPD-Nec-0253
NCU05622
Q7S5Y4
arg-15; NCU05622
21
iEKPD-Nec-0226
NCU08357
Q7SGQ8
cac-2; NCU08357
22
iEKPD-Nec-0227
NCU00202
Q7RXM4
crn; NCU00202
23
iEKPD-Nec-0199
NCU04540
Q7RWG8
fwd-1; NCU04540
24
iEKPD-Nec-0191
NCU07521
Q7S199
fwd-2; NCU07521
25
iEKPD-Nec-0203
NCU00440
F5HH30
gnb-1; NCU00440
26
iEKPD-Nec-0218
NCU08741
Q7SCF4
ham-3; NCU08741
27
iEKPD-Nec-0250
NCU08484
Q1K8G8
mus-27; NCU08484
28
iEKPD-Nec-0263
NCU00560
Q7SF89
NCU00560
29
iEKPD-Nec-0244
NCU00621
Q7SI31
NCU00621
30
iEKPD-Nec-0186
NCU00794
Q7SFT7
NCU00794
31
iEKPD-Nec-0221
NCU00879
V5IQ04
NCU00879
32
iEKPD-Nec-0213
NCU00880
Q7SFF1
NCU00880
33
iEKPD-Nec-0223
NCU01269
Q7S7C3
NCU01269
34
iEKPD-Nec-0248
NCU01367
Q1K6N0
NCU01367
35
iEKPD-Nec-0229
NCU01389
Q1K6Z6
NCU01389
36
iEKPD-Nec-0228
NCU01569
Q1K4X0
NCU01569
37
iEKPD-Nec-0276
NCU01572
Q7RWW5
NCU01572
38
iEKPD-Nec-0209
NCU01595
F5HCE4
NCU01595
39
iEKPD-Nec-0259
NCU02104
Q7SDM9
NCU02104
40
iEKPD-Nec-0261
NCU02112
Q7SDM2
NCU02112
41
iEKPD-Nec-0242
NCU02151
Q7SER5
NCU02151
42
iEKPD-Nec-0238
NCU02477
Q7SG87
NCU02477
43
iEKPD-Nec-0264
NCU02570
Q7SHP5
NCU02570
44
iEKPD-Nec-0273
NCU02604
Q7SG16
NCU02604
45
iEKPD-Nec-0241
NCU02616
Q7SG04
NCU02616
46
iEKPD-Nec-0230
NCU02729
Q7SGC0
NCU02729
47
iEKPD-Nec-0236
NCU02753
Q7SCY1
NCU02753
48
iEKPD-Nec-0271
NCU02781
Q7SE13
NCU02781
49
iEKPD-Nec-0200
NCU02966
Q1K953
NCU02966
50
iEKPD-Nec-0192
NCU03051
Q7SCL0
NCU03051
51
iEKPD-Nec-0194
NCU03244
Q7SCM7
NCU03244
52
iEKPD-Nec-0233
NCU03517
Q7RVN5
NCU03517
53
iEKPD-Nec-0246
NCU03668
Q1K814
NCU03668
54
iEKPD-Nec-0206
NCU03944
Q7RZB7
NCU03944
55
iEKPD-Nec-0270
NCU03965
V5IL09
NCU03965
56
iEKPD-Nec-0239
NCU04101
Q7S7H8
NCU04101
57
iEKPD-Nec-0207
NCU04136
Q1K7L8
NCU04136
58
iEKPD-Nec-0216
NCU04176
Q1K7E9
NCU04176
59
iEKPD-Nec-0210
NCU04281
Q1K788
NCU04281
60
iEKPD-Nec-0257
NCU04288
Q7S7P1
NCU04288
61
iEKPD-Nec-0265
NCU04376
V5INM0
NCU04376
62
iEKPD-Nec-0252
NCU05300
Q7S900
NCU05300
63
iEKPD-Nec-0201
NCU05797
Q7S5P6
NCU05797
64
iEKPD-Nec-0190
NCU05939
Q7S2D9
NCU05939
65
iEKPD-Nec-0220
NCU06039
Q7S4E6
NCU06039
66
iEKPD-Nec-0197
NCU06483
Q7RYJ1
NCU06483
67
iEKPD-Nec-0237
NCU06489
Q7RYI5
NCU06489
68
iEKPD-Nec-0272
NCU06758
Q1K8T1
NCU06758
69
iEKPD-Nec-0262
NCU06838
Q1K8X0
NCU06838
70
iEKPD-Nec-0219
NCU06921
Q7S3D2
NCU06921
71
iEKPD-Nec-0231
NCU07011
Q7S8D5
NCU07011
72
iEKPD-Nec-0204
NCU07319
Q7SA43
NCU07319
73
iEKPD-Nec-0234
NCU07492
Q7SG50
NCU07492
74
iEKPD-Nec-0256
NCU07864
Q7SBU5
NCU07864
75
iEKPD-Nec-0254
NCU07885
Q7SB08
NCU07885
76
iEKPD-Nec-0251
NCU08485
Q1K8G7
NCU08485
77
iEKPD-Nec-0258
NCU08632
Q7SFI9
NCU08632
78
iEKPD-Nec-0217
NCU09162
U9W2M0
NCU09162
79
iEKPD-Nec-0247
NCU09208
Q1K6D4
NCU09208
80
iEKPD-Nec-0275
NCU09432
V5IKR4
NCU09432
81
iEKPD-Nec-0243
NCU09521
Q7S1P4
NCU09521
82
iEKPD-Nec-0245
NCU09744
Q7SEI1
NCU09744
83
iEKPD-Nec-0255
NCU09819
Q7SCP8
NCU09819
84
iEKPD-Nec-0222
NCU09843
Q7S0G9
NCU09843
85
iEKPD-Nec-0205
NCU10066
Q7S028
NCU10066
86
iEKPD-Nec-0208
NCU11251
V5IRK9
NCU11251
87
iEKPD-Nec-0268
NCU11357
A7UWZ9
NCU11357
88
iEKPD-Nec-0232
NCU07662
Q1K8F8
pex7; NCU07662
89
iEKPD-Nec-0198
NCU03628
Q1K7Q6
pod-5; NCU03628
90
iEKPD-Nec-0266
NCU09377
V5IPN6
rgb-1; NCU09377
91
iEKPD-Nec-0269
NCU09142
Q7S2K7
ro-6; NCU09142
92
iEKPD-Nec-0290
NCU06626
Q7S9P0
stk-45; NCU06626
93
iEKPD-Nec-0277
NCU07409
Q7S0U6
TRM82; NCU07409