Sorghum bicolor      pY/C2


※ C2 family introduction

    A C2 domain is a protein structural domain involved in targeting proteins to cell membranes. The typical version (PKC-C2) has a beta-sandwich composed of 8 beta-strands that co-ordinates two or three calcium ions, which bind in a cavity formed by the first and final loops of the domain, on the membrane binding face. The C2 domain of PRKCQ, the closest relative of PRKCQ in the PKC family, was found to be a novel Tyr(P)-binding domain, which could specifically bind a Tyr(P)-containing peptide derived from CDCP1, a protein known to be phosphorylated on tyrosine by activated Src kinase (1).

Reference
1. Stahelin, R.V. (2012) PRKCQ C2 domain is a phosphotyrosine binding module that plays a key role in its activation . J Biol Chem, 287, 30518-28. PMID: 22787157


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sob-1470
SORBI_3002G303300
C5X8K8
SORBI_3002G303300
2
iEKPD-Sob-1469
SORBI_3002G393700
A0A1B6QFU3
SORBI_3002G393700
3
iEKPD-Sob-1467
SORBI_3006G238700
C5Y914
SORBI_3006G238700
4
iEKPD-Sob-1468
SORBI_3006G280300
A0A1Z5RG18
SORBI_3006G280300