※ Other family introduction

    RKIP contains a novel phospho-amino acid binding domain. Substitutions in the ligand binding site of RKIP compromise the stability of the phosphorylated Raf-RKIP complex. Notably, PKM2 binds directly and selectively to tyrosine (Tyr, Y)-phosphorylated peptides, and expression of the phosphotyrosine-binding form of PKM2 is required for the rapid growth of cancer cells (1).
1. Kaneko T, Joshi R, Li SS. (2012) Phosphotyrosine recognition domains: the typical, the atypical and the versatile. Cell Commun Signal, 10(1), 32. PMID: 23134684

  Reviewed (0)  or Unreviewed (9) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mim-1235	ENSMICG00000007458.3
2		iEKPD-Mim-1236	ENSMICG00000010454.3
3		iEKPD-Mim-1237	ENSMICG00000011578.3
4		iEKPD-Mim-1262	ENSMICG00000011844.3
5		iEKPD-Mim-1238	ENSMICG00000031997.2
6		iEKPD-Mim-1239	ENSMICG00000033263.2
7		iEKPD-Mim-1240	ENSMICG00000034007.2
8		iEKPD-Mim-1241	ENSMICG00000037886.2
9		iEKPD-Mim-a001	ENSMICG00000013532.3