※ Other family introduction

    RKIP contains a novel phospho-amino acid binding domain. Substitutions in the ligand binding site of RKIP compromise the stability of the phosphorylated Raf-RKIP complex. Notably, PKM2 binds directly and selectively to tyrosine (Tyr, Y)-phosphorylated peptides, and expression of the phosphotyrosine-binding form of PKM2 is required for the rapid growth of cancer cells (1).
1. Kaneko T, Joshi R, Li SS. (2012) Phosphotyrosine recognition domains: the typical, the atypical and the versatile. Cell Commun Signal, 10(1), 32. PMID: 23134684

  Reviewed (0)  or Unreviewed (4) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sei-1832	Si001951m.g	K3XJ78	LOC101765172; SETIT_001951mg
2		iEKPD-Sei-a004	Si021784m.g	K3Z5G6	LOC101768352; SETIT_021784mg
3		iEKPD-Sei-1833	Si010453m.g	K3Y8B2	LOC101780066; SETIT_010453mg
4		iEKPD-Sei-1834	Si016800m.g	K3YRA6	LOC101786077; SETIT_016800mg