※ Other family introduction

    RKIP contains a novel phospho-amino acid binding domain. Substitutions in the ligand binding site of RKIP compromise the stability of the phosphorylated Raf-RKIP complex. Notably, PKM2 binds directly and selectively to tyrosine (Tyr, Y)-phosphorylated peptides, and expression of the phosphotyrosine-binding form of PKM2 is required for the rapid growth of cancer cells (1).
1. Kaneko T, Joshi R, Li SS. (2012) Phosphotyrosine recognition domains: the typical, the atypical and the versatile. Cell Commun Signal, 10(1), 32. PMID: 23134684

  Reviewed (1)  or Unreviewed (7) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sus-1251	ENSSSCG00000011033.3	P02543	VIM
2		iEKPD-Sus-1249	ENSSSCG00000006126.3	D6QST6	DECR1
3		iEKPD-Sus-1252	ENSSSCG00000021977.2	I3LLU0	GPD1L
4		iEKPD-Sus-1254	ENSSSCG00000038708.1	A0A286ZUS0	LOC102167410
5		iEKPD-Sus-1250	ENSSSCG00000009851.3	F1RKG8	PEBP1
6		iEKPD-Sus-1253	ENSSSCG00000026149.2	A0A286ZYV7	PKLR
7		iEKPD-Sus-a001	ENSSSCG00000001930.3	A0A287B8G0	PKM
8		iEKPD-Sus-1296	ENSSSCG00000034154.1	A0A286ZKV7	WNK2