※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253

  Reviewed (7)  or Unreviewed (4) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Cae-0635	WBGene00000420	O76337	ced-6; F56D2.7
2		iEKPD-Cae-0637	WBGene00001116	Q8STF6	dyc-1; C33G3.1
3		iEKPD-Cae-0844	WBGene00001410	Q9BKZ9	feh-1; Y54F10AM.2
4		iEKPD-Cae-0842	WBGene00002999	O17583	lin-10; C09H6.2
5		iEKPD-Cae-0634	WBGene00003830	Q9XTY6	num-1; cka-1; T03D8.1
6		iEKPD-Cae-0845	WBGene00018788	Q9TYT3	shc-1; F54A5.3
7		iEKPD-Cae-0837	WBGene00006508	P91301	tag-83; F46F11.3
8		iEKPD-Cae-0639	WBGene00007520	Q93203	C11E4.6; CELE_C11E4.6
9		iEKPD-Cae-0636	WBGene00000894	A5JYR4	dab-1; CELE_M110.5; M110.5
10		iEKPD-Cae-0638	WBGene00002176	G4RZC8	jip-1; CELE_F56D12.4; F56D12.4
11		iEKPD-Cae-0640	WBGene00018819	E6N0V1	rog-1; CELE_F54D12.6; F54D12.6