Carlito syrichta      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cas-0816
ENSTSYG00000007562.2
A0A1U7TUC5
ANKS1A
2
iEKPD-Cas-0824
ENSTSYG00000036582.1
A0A1U7T262
ANKS1B
3
iEKPD-Cas-1252
ENSTSYG00000012255.2
A0A1U7TRE5
APBA1
4
iEKPD-Cas-1254
ENSTSYG00000000341.2
A0A1U7TJH4
APBA2
5
iEKPD-Cas-1257
ENSTSYG00000026012.1
A0A1U7TS60
APBB1
6
iEKPD-Cas-1260
ENSTSYG00000000597.2
A0A1U7TD50
APBB3
7
iEKPD-Cas-0814
ENSTSYG00000002713.2
A0A1U7UCD7
APPL1
8
iEKPD-Cas-0821
ENSTSYG00000003427.2
A0A1U7V3M7
APPL2
9
iEKPD-Cas-0826
ENSTSYG00000005263.2
A0A1U7TE55
DAB1
10
iEKPD-Cas-0815
ENSTSYG00000003683.2
A0A1U7U407
DAB2
11
iEKPD-Cas-0822
ENSTSYG00000031435.1
A0A1U7SLI3
DOK1
12
iEKPD-Cas-0825
ENSTSYG00000033054.1
A0A1U7UTH1
DOK2
13
iEKPD-Cas-0823
ENSTSYG00000035383.1
A0A1U7ULN1
DOK4
14
iEKPD-Cas-0819
ENSTSYG00000006310.2
A0A1U7TFN4
DOK5
15
iEKPD-Cas-0820
ENSTSYG00000005856.2
A0A1U7UBE3
DOK6
16
iEKPD-Cas-0817
ENSTSYG00000009637.2
A0A1U7UAG2
EPS8
17
iEKPD-Cas-0831
ENSTSYG00000028915.1
A0A1U7TUL6
FAM43A
18
iEKPD-Cas-0828
ENSTSYG00000035362.1
A0A1U7U3Z0
FRS2
19
iEKPD-Cas-0830
ENSTSYG00000001230.2
A0A1U7U669
FRS3
20
iEKPD-Cas-0832
ENSTSYG00000003394.2
A0A1U7TJJ5
IRS4
21
iEKPD-Cas-0818
ENSTSYG00000014537.2
A0A1U7UU35
ITGB1BP1
22
iEKPD-Cas-0811
ENSTSYG00000029173.1
A0A1U7UG80
LDLRAP1
23
iEKPD-Cas-0813
ENSTSYG00000031186.1
A0A1U7TEH7
LOC103258944
24
iEKPD-Cas-0812
ENSTSYG00000007612.2
A0A1U7TU32
LOC103265487
25
iEKPD-Cas-0809
ENSTSYG00000026119.1
A0A1U7SMJ3
MAPK8IP1
26
iEKPD-Cas-0810
ENSTSYG00000030340.1
A0A1U7UHS7
MAPK8IP2
27
iEKPD-Cas-0829
ENSTSYG00000009370.2
A0A1U7UNF4
NOS1AP
28
iEKPD-Cas-0807
ENSTSYG00000010352.2
A0A1U7UCD0
NUMB
29
iEKPD-Cas-0808
ENSTSYG00000030270.1
A0A1U7TC93
NUMBL
30
iEKPD-Cas-0833
ENSTSYG00000007863.2
A0A1U7UIC1
PID1
31
iEKPD-Cas-1255
ENSTSYG00000008995.2
A0A1U7UFF4
RGS12
32
iEKPD-Cas-1259
ENSTSYG00000011380.2
A0A1U7SRJ2
SHC1
33
iEKPD-Cas-1258
ENSTSYG00000014697.2
A0A1U7UD95
SHC4
34
iEKPD-Cas-0827
ENSTSYG00000006256.2
A0A1U7TXQ7
TBC1D4
35
iEKPD-Cas-1235
ENSTSYG00000035447.1
A0A1U7U5X8
TENC1
36
iEKPD-Cas-1232
ENSTSYG00000008446.2
A0A1U7UT19
TNS1
37
iEKPD-Cas-1233
ENSTSYG00000012028.2
A0A1U7U5W9
TNS3
38
iEKPD-Cas-1261
ENSTSYG00000000681.2
A0A1U7U3N8
TNS4