Cavia porcellus      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 49 genes.  Reviewed (0 or Unreviewed (49

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cap-0861
ENSCPOG00000033292.1
2
iEKPD-Cap-0862
ENSCPOG00000008684.4
3
iEKPD-Cap-1315
ENSCPOG00000006525.4
H0V7Z6
4
iEKPD-Cap-0881
ENSCPOG00000006835.4
H0V8P8
5
iEKPD-Cap-0865
ENSCPOG00000015430.4
A0A286X7I6
ANKS1A
6
iEKPD-Cap-0864
ENSCPOG00000015197.4
H0VST1
ANKS1B
7
iEKPD-Cap-1305
ENSCPOG00000032780.1
A0A286XHZ6
APBA1
8
iEKPD-Cap-1306
ENSCPOG00000002505.4
H0UYR0
APBA2
9
iEKPD-Cap-0863
ENSCPOG00000026376.2
H0VVS0
Apba3
10
iEKPD-Cap-1310
ENSCPOG00000019866.2
H0VWA1
APBB1
11
iEKPD-Cap-1311
ENSCPOG00000006689.4
H0V8C9
APBB2
12
iEKPD-Cap-1313
ENSCPOG00000006384.4
H0V7N4
APBB3
13
iEKPD-Cap-0859
ENSCPOG00000007758.4
H0VAT4
APPL1
14
iEKPD-Cap-0867
ENSCPOG00000010211.4
H0VGD7
APPL2
15
iEKPD-Cap-0860
ENSCPOG00000005440.4
H0V5G6
DAB1
16
iEKPD-Cap-0871
ENSCPOG00000038650.1
A0A286XBV6
DOK1
17
iEKPD-Cap-0876
ENSCPOG00000001726.4
H0UWV9
DOK2
18
iEKPD-Cap-0882
ENSCPOG00000008758.4
H0VD24
DOK3
19
iEKPD-Cap-0870
ENSCPOG00000035700.1
A0A286XL26
DOK4
20
iEKPD-Cap-0868
ENSCPOG00000012780.4
H0VM80
DOK5
21
iEKPD-Cap-0869
ENSCPOG00000003225.4
H0V0D4
DOK6
22
iEKPD-Cap-0885
ENSCPOG00000020197.2
H0W434
DOK7
23
iEKPD-Cap-0866
ENSCPOG00000012163.4
A0A286XEH4
EPS8
24
iEKPD-Cap-0877
ENSCPOG00000003802.4
H0V1Q3
EPS8L2
25
iEKPD-Cap-0883
ENSCPOG00000021729.2
H0WDI8
FAM43A
26
iEKPD-Cap-0880
ENSCPOG00000002836.4
H0UZH3
FRS2
27
iEKPD-Cap-0879
ENSCPOG00000009128.4
H0VDX2
FRS3
28
iEKPD-Cap-0854
ENSCPOG00000010495.4
A0A286XRU4
GULP1
29
iEKPD-Cap-0875
ENSCPOG00000005422.4
H0V5F0
IRS1
30
iEKPD-Cap-0884
ENSCPOG00000007683.4
H0VAN4
IRS4
31
iEKPD-Cap-0872
ENSCPOG00000010293.4
H0VGJ9
ITGB1BP1
32
iEKPD-Cap-0858
ENSCPOG00000038658.1
A0A286Y0L1
LDLRAP1
33
iEKPD-Cap-0856
ENSCPOG00000001298.4
A0A286Y3C4
MAPK8IP1
34
iEKPD-Cap-0857
ENSCPOG00000040518.1
A0A286XZA0
MAPK8IP2
35
iEKPD-Cap-0878
ENSCPOG00000008808.4
H0VD63
NOS1AP
36
iEKPD-Cap-0853
ENSCPOG00000034984.1
A0A286Y575
NUMB
37
iEKPD-Cap-0855
ENSCPOG00000024225.2
H0WDF9
NUMBL
38
iEKPD-Cap-0886
ENSCPOG00000037556.1
A0A286XRT0
PID1
39
iEKPD-Cap-0887
ENSCPOG00000009811.4
H0VFG3
RABGAP1
40
iEKPD-Cap-1307
ENSCPOG00000005334.4
A0A286XJR1
RGS12
41
iEKPD-Cap-1312
ENSCPOG00000024934.2
H0W707
SHC1
42
iEKPD-Cap-1314
ENSCPOG00000026631.2
H0W2L0
Shc2
43
iEKPD-Cap-1316
ENSCPOG00000019862.2
H0W5G3
SHC3
44
iEKPD-Cap-0874
ENSCPOG00000013615.4
A0A286XJG5
TBC1D1
45
iEKPD-Cap-0873
ENSCPOG00000010658.4
H0VHD9
TBC1D4
46
iEKPD-Cap-1283
ENSCPOG00000001411.4
A0A286XTS9
TNS1
47
iEKPD-Cap-1286
ENSCPOG00000024457.2
H0WA34
TNS2
48
iEKPD-Cap-1285
ENSCPOG00000005141.4
A0A286XZL3
TNS3
49
iEKPD-Cap-1317
ENSCPOG00000010254.4
H0VGG7
TNS4