Equus caballus      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 44 genes.  Reviewed (0 or Unreviewed (44

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Eqc-0824
ENSECAG00000017304.1
F7AYQ5
2
iEKPD-Eqc-0828
ENSECAG00000011449.1
F7BGK6
3
iEKPD-Eqc-0844
ENSECAG00000022553.1
F7B2X2
4
iEKPD-Eqc-0829
ENSECAG00000019918.1
F7DGV1
ANKS1A
5
iEKPD-Eqc-1268
ENSECAG00000000271.1
F7DTH7
APBA1
6
iEKPD-Eqc-1270
ENSECAG00000015516.1
F6VY08
APBA2
7
iEKPD-Eqc-1269
ENSECAG00000021308.1
F6T8B1
APBA3
8
iEKPD-Eqc-1272
ENSECAG00000014015.1
F7DGI1
APBB1
9
iEKPD-Eqc-1273
ENSECAG00000020719.1
F6U869
APBB2
10
iEKPD-Eqc-1277
ENSECAG00000003436.1
F6PPR9
APBB3
11
iEKPD-Eqc-0826
ENSECAG00000017473.1
F6PPE5
APPL1
12
iEKPD-Eqc-0833
ENSECAG00000020564.1
F6UBU6
APPL2
13
iEKPD-Eqc-0825
ENSECAG00000011414.1
F7AIX3
DAB1
14
iEKPD-Eqc-0827
ENSECAG00000013597.1
F7AET6
DAB2
15
iEKPD-Eqc-0835
ENSECAG00000022646.1
F6U2E6
DOK1
16
iEKPD-Eqc-0837
ENSECAG00000023145.1
F6WCN4
DOK2
17
iEKPD-Eqc-0836
ENSECAG00000018550.1
F6ZA59
DOK4
18
iEKPD-Eqc-0834
ENSECAG00000023012.1
F6UFR0
DOK5
19
iEKPD-Eqc-0831
ENSECAG00000003159.1
F6X614
DOK6
20
iEKPD-Eqc-0830
ENSECAG00000014922.1
F7D5Z7
EPS8
21
iEKPD-Eqc-0840
ENSECAG00000011484.1
F7BFV0
EPS8L2
22
iEKPD-Eqc-0843
ENSECAG00000020194.1
F7DHM8
FRS2
23
iEKPD-Eqc-0842
ENSECAG00000015081.1
F7C413
FRS3
24
iEKPD-Eqc-0821
ENSECAG00000023352.1
F6W3H5
GULP1
25
iEKPD-Eqc-0838
ENSECAG00000007393.1
F7DIR1
IRS1
26
iEKPD-Eqc-0846
ENSECAG00000011649.1
F7BFW6
IRS4
27
iEKPD-Eqc-0832
ENSECAG00000024193.1
F6X476
ITGB1BP1
28
iEKPD-Eqc-0823
ENSECAG00000019441.1
F7E2W7
LDLRAP1
29
iEKPD-Eqc-0822
ENSECAG00000007619.1
F7DZZ0
MAPK8IP1
30
iEKPD-Eqc-0841
ENSECAG00000016715.1
F6WUQ0
NOS1AP
31
iEKPD-Eqc-0819
ENSECAG00000016684.1
F6YXJ9
NUMB
32
iEKPD-Eqc-0820
ENSECAG00000017299.1
F6PSV5
NUMBL
33
iEKPD-Eqc-0847
ENSECAG00000011829.1
F6ZXS2
PID1
34
iEKPD-Eqc-1271
ENSECAG00000019746.1
F7E0X7
RGS12
35
iEKPD-Eqc-1279
ENSECAG00000013721.1
F7BBV0
SH2D5
36
iEKPD-Eqc-1275
ENSECAG00000003967.1
F6ZGT4
SHC1
37
iEKPD-Eqc-1276
ENSECAG00000023729.1
F7E4E1
SHC3
38
iEKPD-Eqc-1274
ENSECAG00000015163.1
F7DS04
SHC4
39
iEKPD-Eqc-0839
ENSECAG00000022162.1
F7B8C2
TBC1D1
40
iEKPD-Eqc-0845
ENSECAG00000016417.1
F6YLM6
TBC1D4
41
iEKPD-Eqc-1249
ENSECAG00000014711.1
F6U920
TNS1
42
iEKPD-Eqc-1250
ENSECAG00000010909.1
F7BIK2
TNS2
43
iEKPD-Eqc-1247
ENSECAG00000020052.1
F7DBQ5
TNS3
44
iEKPD-Eqc-1278
ENSECAG00000007918.1
F6VZB0
TNS4