Erinaceus europaeus      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 31 genes.  Reviewed (0 or Unreviewed (31

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ere-0651
ENSEEUG00000001135.1
2
iEKPD-Ere-0656
ENSEEUG00000014437.1
3
iEKPD-Ere-0966
ENSEEUG00000002247.1
A0A1S3AQH0
APBA1
4
iEKPD-Ere-0637
ENSEEUG00000007320.1
A0A1S3WLC9
APBA2
5
iEKPD-Ere-0969
ENSEEUG00000005037.1
A0A1S2ZZM3
APBB2
6
iEKPD-Ere-0648
ENSEEUG00000007666.1
A0A1S3W4H5
APBB3
7
iEKPD-Ere-0972
ENSEEUG00000014791.1
A0A1S3W5L2
APBB3
8
iEKPD-Ere-0657
ENSEEUG00000006733.1
A0A1S2ZD71
APBB3
9
iEKPD-Ere-0649
ENSEEUG00000015640.1
A0A1S2ZLL1
APPL1
10
iEKPD-Ere-0644
ENSEEUG00000002723.1
A0A1S3AD01
APPL2
11
iEKPD-Ere-0640
ENSEEUG00000003484.1
A0A1S2ZEB1
DAB1
12
iEKPD-Ere-0654
ENSEEUG00000005476.1
A0A1S2ZDD8
DAB2
13
iEKPD-Ere-0643
ENSEEUG00000009110.1
A0A1S2ZRG9
DOK1
14
iEKPD-Ere-0647
ENSEEUG00000004679.1
A0A1S3A4E7
DOK2
15
iEKPD-Ere-0645
ENSEEUG00000003729.1
A0A1S2ZJ72
DOK4
16
iEKPD-Ere-0641
ENSEEUG00000012287.1
A0A1S2ZT10
DOK6
17
iEKPD-Ere-0650
ENSEEUG00000015057.1
A0A1S3A5V8
FRS3
18
iEKPD-Ere-0653
ENSEEUG00000002551.1
A0A1S3A455
GULP1
19
iEKPD-Ere-0655
ENSEEUG00000005100.1
A0A1S3A7F9
IRS4
20
iEKPD-Ere-0642
ENSEEUG00000015370.1
A0A1S2ZNY4
ITGB1BP1
21
iEKPD-Ere-0638
ENSEEUG00000001531.1
A0A1S2ZPP1
LDLRAP1
22
iEKPD-Ere-0646
ENSEEUG00000004608.1
A0A1S2ZHF1
MAPK8IP2
23
iEKPD-Ere-0652
ENSEEUG00000001629.1
A0A1S3ADP1
NOS1AP
24
iEKPD-Ere-0639
ENSEEUG00000007572.1
A0A1S2ZMU7
NUMB
25
iEKPD-Ere-0971
ENSEEUG00000013016.1
A0A1S3WDI9
SHC2
26
iEKPD-Ere-0968
ENSEEUG00000014866.1
A0A1S3ASN0
SHC3
27
iEKPD-Ere-0970
ENSEEUG00000012551.1
A0A1S2ZCR6
SHC4
28
iEKPD-Ere-0951
ENSEEUG00000007106.1
A0A1S3W987
TNS1
29
iEKPD-Ere-0953
ENSEEUG00000008855.1
A0A1S2ZER0
TNS2
30
iEKPD-Ere-0957
ENSEEUG00000007808.1
A0A1S2ZU72
TNS3
31
iEKPD-Ere-0973
ENSEEUG00000008880.1
A0A1S3A8P3
TNS4