Felis catus      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 48 genes.  Reviewed (0 or Unreviewed (48

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fec-1299
ENSFCAG00000014623.4
M3WL11
2
iEKPD-Fec-0843
ENSFCAG00000040012.1
A0A2I2UGZ5
3
iEKPD-Fec-0844
ENSFCAG00000005884.4
A0A2I2URT8
4
iEKPD-Fec-0861
ENSFCAG00000026820.2
M3X4G3
5
iEKPD-Fec-1300
ENSFCAG00000008067.4
A0A2I2UQF7
APBA2
6
iEKPD-Fec-1301
ENSFCAG00000019172.3
M3WPC7
APBA3
7
iEKPD-Fec-1305
ENSFCAG00000004628.4
M3W2J3
APBB1
8
iEKPD-Fec-1306
ENSFCAG00000012843.4
A0A2I2U9K6
APBB2
9
iEKPD-Fec-1310
ENSFCAG00000001276.4
M3VWC4
APBB3
10
iEKPD-Fec-0841
ENSFCAG00000018631.3
A0A2I2UME8
APPL1
11
iEKPD-Fec-0846
ENSFCAG00000001461.4
M3VWP5
APPL2
12
iEKPD-Fec-0840
ENSFCAG00000003901.4
A0A2I2U6M3
DAB1
13
iEKPD-Fec-0842
ENSFCAG00000013125.4
M3WI97
DAB2
14
iEKPD-Fec-0850
ENSFCAG00000007159.2
M3W784
DOK1
15
iEKPD-Fec-0856
ENSFCAG00000008964.4
M3WAJ3
DOK2
16
iEKPD-Fec-0860
ENSFCAG00000026604.2
M3X6K9
DOK3
17
iEKPD-Fec-0851
ENSFCAG00000004698.4
M3W2N6
DOK4
18
iEKPD-Fec-0848
ENSFCAG00000007809.3
M3W8F3
DOK5
19
iEKPD-Fec-0847
ENSFCAG00000004167.4
M3W1P6
DOK6
20
iEKPD-Fec-0865
ENSFCAG00000012716.4
A0A2I2U7K1
DOK7
21
iEKPD-Fec-0845
ENSFCAG00000023054.2
M3WSY6
EPS8
22
iEKPD-Fec-0857
ENSFCAG00000025509.2
M3X4X2
EPS8L1
23
iEKPD-Fec-0853
ENSFCAG00000030367.2
A0A2I2UB40
EPS8L2
24
iEKPD-Fec-0862
ENSFCAG00000004000.3
M3W1D2
FAM43A
25
iEKPD-Fec-0859
ENSFCAG00000034591.1
A0A2I2UYY5
FRS2
26
iEKPD-Fec-0858
ENSFCAG00000014739.3
M3WL89
FRS3
27
iEKPD-Fec-0834
ENSFCAG00000024177.2
A0A2I2V543
GULP1
28
iEKPD-Fec-0854
ENSFCAG00000003009.3
M3WUW8
IRS1
29
iEKPD-Fec-0863
ENSFCAG00000000760.3
M3VVC7
IRS4
30
iEKPD-Fec-0849
ENSFCAG00000034320.1
A0A2I2UGY4
ITGB1BP1
31
iEKPD-Fec-0839
ENSFCAG00000036460.1
A0A2I2UTI2
LDLRAP1
32
iEKPD-Fec-0838
ENSFCAG00000003189.4
M3VZW4
MAPK8IP1
33
iEKPD-Fec-0837
ENSFCAG00000027869.2
M3X4P2
MAPK8IP2
34
iEKPD-Fec-0852
ENSFCAG00000014120.3
M3WK36
NOS1AP
35
iEKPD-Fec-0835
ENSFCAG00000026244.2
A0A2I2UDS5
NUMB
36
iEKPD-Fec-0836
ENSFCAG00000004467.4
M3W286
NUMBL
37
iEKPD-Fec-0864
ENSFCAG00000037409.1
A0A2I2U1V1
PID1
38
iEKPD-Fec-0866
ENSFCAG00000004092.4
M3W1J8
RABGAP1
39
iEKPD-Fec-1302
ENSFCAG00000004612.4
M3W2I7
RGS12
40
iEKPD-Fec-1312
ENSFCAG00000000800.4
M3VVF2
SH2D5
41
iEKPD-Fec-1307
ENSFCAG00000001346.4
M3VWH1
SHC1
42
iEKPD-Fec-1309
ENSFCAG00000015438.3
A0A2I2V2S2
SHC2
43
iEKPD-Fec-1308
ENSFCAG00000004212.4
M3W1S4
SHC3
44
iEKPD-Fec-0855
ENSFCAG00000009063.4
M3WAQ9
TBC1D1
45
iEKPD-Fec-1279
ENSFCAG00000001073.4
A0A2I2V1I8
TNS1
46
iEKPD-Fec-1280
ENSFCAG00000000304.4
A0A2I2UCC5
TNS2
47
iEKPD-Fec-1281
ENSFCAG00000007717.4
A0A2I2V1A6
TNS3
48
iEKPD-Fec-1311
ENSFCAG00000009644.4
M3WBU0
TNS4