※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253

  Reviewed (1)  or Unreviewed (44) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mim-0856	ENSMICG00000003540.3	Q2QL84	ASZ1; GASZ
2		iEKPD-Mim-1314	ENSMICG00000038165.2
3		iEKPD-Mim-1315	ENSMICG00000011164.3
4		iEKPD-Mim-1309	ENSMICG00000009602.3
5		iEKPD-Mim-1310	ENSMICG00000006447.3
6		iEKPD-Mim-1316	ENSMICG00000007933.3
7		iEKPD-Mim-1317	ENSMICG00000036874.2
8		iEKPD-Mim-1318	ENSMICG00000035080.2
9		iEKPD-Mim-0847	ENSMICG00000016453.3
10		iEKPD-Mim-0848	ENSMICG00000017925.3
11		iEKPD-Mim-0849	ENSMICG00000035552.2
12		iEKPD-Mim-1311	ENSMICG00000014756.3
13		iEKPD-Mim-1319	ENSMICG00000004066.3
14		iEKPD-Mim-0850	ENSMICG00000000871.3
15		iEKPD-Mim-0851	ENSMICG00000047758.1
16		iEKPD-Mim-0852	ENSMICG00000014190.3
17		iEKPD-Mim-1320	ENSMICG00000000372.3
18		iEKPD-Mim-0853	ENSMICG00000005574.3
19		iEKPD-Mim-0854	ENSMICG00000000730.3
20		iEKPD-Mim-0855	ENSMICG00000006730.3
21		iEKPD-Mim-1288	ENSMICG00000014125.3
22		iEKPD-Mim-0857	ENSMICG00000014070.3
23		iEKPD-Mim-0858	ENSMICG00000001968.3
24		iEKPD-Mim-1286	ENSMICG00000009472.3
25		iEKPD-Mim-0859	ENSMICG00000004144.3
26		iEKPD-Mim-0860	ENSMICG00000014454.3
27		iEKPD-Mim-1289	ENSMICG00000017467.3
28		iEKPD-Mim-0861	ENSMICG00000002359.3
29		iEKPD-Mim-0862	ENSMICG00000027937.2
30		iEKPD-Mim-0863	ENSMICG00000000045.3
31		iEKPD-Mim-0864	ENSMICG00000047288.1
32		iEKPD-Mim-0865	ENSMICG00000004679.3
33		iEKPD-Mim-1321	ENSMICG00000009811.3
34		iEKPD-Mim-0866	ENSMICG00000028364.2
35		iEKPD-Mim-0867	ENSMICG00000009504.3
36		iEKPD-Mim-1312	ENSMICG00000007623.3
37		iEKPD-Mim-0868	ENSMICG00000011568.3
38		iEKPD-Mim-0869	ENSMICG00000001611.3
39		iEKPD-Mim-0870	ENSMICG00000011467.3
40		iEKPD-Mim-0871	ENSMICG00000006286.3
41		iEKPD-Mim-0872	ENSMICG00000036406.2
42		iEKPD-Mim-0873	ENSMICG00000016893.3
43		iEKPD-Mim-0874	ENSMICG00000037622.2
44		iEKPD-Mim-0875	ENSMICG00000012692.3
45		iEKPD-Mim-0876	ENSMICG00000014596.3