Myotis lucifugus      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 46 genes.  Reviewed (0 or Unreviewed (46

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Myl-0840
ENSMLUG00000016048.2
G1PTQ4
2
iEKPD-Myl-1303
ENSMLUG00000027362.1
G1QFM4
3
iEKPD-Myl-0844
ENSMLUG00000025382.1
G1Q5M9
4
iEKPD-Myl-0845
ENSMLUG00000022775.1
G1Q1K3
5
iEKPD-Myl-0859
ENSMLUG00000005662.2
G1P597
6
iEKPD-Myl-1293
ENSMLUG00000007778.2
G1PA16
APBA1
7
iEKPD-Myl-1294
ENSMLUG00000015628.2
G1PSS4
APBA2
8
iEKPD-Myl-1292
ENSMLUG00000010776.2
G1PGQ2
APBA3
9
iEKPD-Myl-1297
ENSMLUG00000012111.2
G1PJV2
APBB1
10
iEKPD-Myl-1298
ENSMLUG00000004853.2
G1P3D2
APBB2
11
iEKPD-Myl-1302
ENSMLUG00000003148.2
G1NZI0
APBB3
12
iEKPD-Myl-0842
ENSMLUG00000000842.2
G1NU89
APPL1
13
iEKPD-Myl-0849
ENSMLUG00000007408.2
G1P990
APPL2
14
iEKPD-Myl-0855
ENSMLUG00000007487.2
G1P9E3
DAB1
15
iEKPD-Myl-0843
ENSMLUG00000005444.2
G1P4S4
DAB2
16
iEKPD-Myl-0861
ENSMLUG00000023882.1
G1QEU9
DOK1
17
iEKPD-Myl-0854
ENSMLUG00000015858.2
G1PTA4
DOK2
18
iEKPD-Myl-0856
ENSMLUG00000006592.2
G1P7C6
DOK3
19
iEKPD-Myl-0851
ENSMLUG00000015839.2
G1PT92
DOK4
20
iEKPD-Myl-0847
ENSMLUG00000009108.2
G1PCX6
DOK5
21
iEKPD-Myl-0846
ENSMLUG00000008202.2
G1PAZ0
DOK6
22
iEKPD-Myl-0848
ENSMLUG00000015815.2
G1PT77
EPS8
23
iEKPD-Myl-0860
ENSMLUG00000001955.2
G1NWR0
FAM43A
24
iEKPD-Myl-0858
ENSMLUG00000003598.2
G1P0J3
FRS2
25
iEKPD-Myl-0857
ENSMLUG00000014002.2
G1PP32
FRS3
26
iEKPD-Myl-0835
ENSMLUG00000007736.2
G1P9X7
GULP1
27
iEKPD-Myl-0853
ENSMLUG00000000967.2
G1Q7F2
IRS1
28
iEKPD-Myl-0863
ENSMLUG00000010704.2
G1PGK3
IRS4
29
iEKPD-Myl-0850
ENSMLUG00000010629.2
G1PGC8
ITGB1BP1
30
iEKPD-Myl-0841
ENSMLUG00000005070.2
G1P3W4
LDLRAP1
31
iEKPD-Myl-0839
ENSMLUG00000014740.2
G1PQP2
MAPK8IP1
32
iEKPD-Myl-0838
ENSMLUG00000010723.2
G1PGK7
MAPK8IP2
33
iEKPD-Myl-0837
ENSMLUG00000015460.2
G1PSE9
NUMB
34
iEKPD-Myl-0836
ENSMLUG00000000395.2
G1NT77
NUMBL
35
iEKPD-Myl-0864
ENSMLUG00000010592.2
G1PG96
PID1
36
iEKPD-Myl-0865
ENSMLUG00000003865.2
G1P152
RABGAP1
37
iEKPD-Myl-1295
ENSMLUG00000003434.2
G1P061
RGS12
38
iEKPD-Myl-1305
ENSMLUG00000011446.2
G1PIA8
SH2D5
39
iEKPD-Myl-1301
ENSMLUG00000002396.2
G1NXS1
SHC1
40
iEKPD-Myl-1300
ENSMLUG00000006630.2
G1P7F4
SHC3
41
iEKPD-Myl-1299
ENSMLUG00000012913.2
G1PLL1
SHC4
42
iEKPD-Myl-0852
ENSMLUG00000004239.2
G1P1Z5
TBC1D1
43
iEKPD-Myl-0862
ENSMLUG00000012131.2
G1PJW7
TBC1D4
44
iEKPD-Myl-1275
ENSMLUG00000007467.2
G1P9F3
TNS1
45
iEKPD-Myl-1276
ENSMLUG00000013033.2
G1PLW2
TNS2
46
iEKPD-Myl-1304
ENSMLUG00000004502.2
G1P2K7
TNS4