※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ora-0817	ENSOANG00000000996.2	F6WN47
2		iEKPD-Ora-0819	ENSOANG00000014174.2	F6PFT4
3		iEKPD-Ora-0824	ENSOANG00000031823.1	K7EHP8
4		iEKPD-Ora-1183	ENSOANG00000003084.3	F6YNK1
5		iEKPD-Ora-0830	ENSOANG00000010250.1	F6ZKE5
6		iEKPD-Ora-0831	ENSOANG00000009122.2	F7F182
7		iEKPD-Ora-1198	ENSOANG00000012954.2	F6ZBA6
8		iEKPD-Ora-0836	ENSOANG00000021593.2	F6Y8C1
9		iEKPD-Ora-0837	ENSOANG00000003509.2	F7FKH8
10		iEKPD-Ora-0839	ENSOANG00000020085.3	F6XK16
11		iEKPD-Ora-0840	ENSOANG00000010316.1	F6SIC0
12		iEKPD-Ora-0842	ENSOANG00000001902.3	F7AQB7
13		iEKPD-Ora-0823	ENSOANG00000005590.3	F6PXV3	ANKS1B
14		iEKPD-Ora-1195	ENSOANG00000002093.2	F6UN75	APBA1
15		iEKPD-Ora-0818	ENSOANG00000010369.2	F7AAW9	APBA2
16		iEKPD-Ora-1193	ENSOANG00000006293.3	F6US59	APBA3
17		iEKPD-Ora-0826	ENSOANG00000020608.2	F7GE74	APBB3
18		iEKPD-Ora-0821	ENSOANG00000001547.2	F7GDI8	APPL1
19		iEKPD-Ora-0827	ENSOANG00000005542.3	F6RTD8	APPL2
20		iEKPD-Ora-0822	ENSOANG00000010205.3	F6RPK2	DAB2
21		iEKPD-Ora-0832	ENSOANG00000013185.3	F7ATG3	DOK2
22		iEKPD-Ora-0829	ENSOANG00000009336.2	F7GC02	DOK4
23		iEKPD-Ora-0825	ENSOANG00000009239.3	F7CEH0	DOK5
24		iEKPD-Ora-0838	ENSOANG00000012743.2	F6V2I0	FAM43A
25		iEKPD-Ora-0843	ENSOANG00000000596.1	F7F3Y3	FAM43B
26		iEKPD-Ora-0834	ENSOANG00000005947.1	F7CJ88	FRS2
27		iEKPD-Ora-0835	ENSOANG00000015437.2	F6TIK8	FRS3
28		iEKPD-Ora-0828	ENSOANG00000006950.3	F7E9S2	ITGB1BP1
29		iEKPD-Ora-0820	ENSOANG00000004861.2	F7G017	LOC100077871
30		iEKPD-Ora-0845	ENSOANG00000008854.2	F7FJ07	LOC100089730
31		iEKPD-Ora-0841	ENSOANG00000031151.1	K7EAM2	LOC100682083
32		iEKPD-Ora-0844	ENSOANG00000022290.2	F6ZIM2	LOC103167875
33		iEKPD-Ora-0833	ENSOANG00000006737.2	F7CSF2	NOS1AP
34		iEKPD-Ora-1197	ENSOANG00000006978.3	F7D8A0	SHC2