Sarcophilus harrisii      pY/PTB


※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253


There are 44 genes.  Reviewed (0 or Unreviewed (44

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sah-0783
ENSSHAG00000004654.1
G3VQ70
2
iEKPD-Sah-0784
ENSSHAG00000009345.1
G3W5Y4
3
iEKPD-Sah-0785
ENSSHAG00000007913.1
G3W134
4
iEKPD-Sah-0787
ENSSHAG00000011922.1
G3WET6
5
iEKPD-Sah-0794
ENSSHAG00000010712.1
G3WAQ7
6
iEKPD-Sah-1217
ENSSHAG00000002156.1
G3VGY0
7
iEKPD-Sah-0807
ENSSHAG00000014939.1
G3WQ82
8
iEKPD-Sah-0808
ENSSHAG00000013165.1
G3WJ39
9
iEKPD-Sah-0788
ENSSHAG00000006146.1
G3VV68
ANKS1A
10
iEKPD-Sah-1215
ENSSHAG00000007996.1
G3W1D3
APBA1
11
iEKPD-Sah-1216
ENSSHAG00000015470.1
G3WS16
APBA2
12
iEKPD-Sah-1214
ENSSHAG00000002223.1
G3VH57
APBA3
13
iEKPD-Sah-1222
ENSSHAG00000006156.1
G3VV80
APBB1
14
iEKPD-Sah-1220
ENSSHAG00000016906.1
G3WWW6
APBB2
15
iEKPD-Sah-1225
ENSSHAG00000016315.1
G3WUV8
APBB3
16
iEKPD-Sah-0786
ENSSHAG00000017105.1
G3WXK9
APPL1
17
iEKPD-Sah-0795
ENSSHAG00000009765.1
G3W7E7
APPL2
18
iEKPD-Sah-0789
ENSSHAG00000001864.1
G3VFZ2
DAB1
19
iEKPD-Sah-0796
ENSSHAG00000016770.1
G3WWE8
DOK1
20
iEKPD-Sah-0801
ENSSHAG00000017704.1
G3WZM1
DOK2
21
iEKPD-Sah-0802
ENSSHAG00000014105.1
G3WMC5
DOK3
22
iEKPD-Sah-0797
ENSSHAG00000015420.1
G3WRV5
DOK4
23
iEKPD-Sah-0791
ENSSHAG00000008979.1
G3W4P5
DOK5
24
iEKPD-Sah-0792
ENSSHAG00000008431.1
G3W2T8
DOK6
25
iEKPD-Sah-0790
ENSSHAG00000014124.1
G3WME8
EPS8
26
iEKPD-Sah-0805
ENSSHAG00000004115.1
G3VND2
FAM43A
27
iEKPD-Sah-0803
ENSSHAG00000004919.1
G3VR24
FRS2
28
iEKPD-Sah-0781
ENSSHAG00000003109.1
G3VK36
GULP1
29
iEKPD-Sah-0798
ENSSHAG00000014636.1
G3WP63
IRS1
30
iEKPD-Sah-0799
ENSSHAG00000014971.1
G3WQC7
IRS2
31
iEKPD-Sah-0804
ENSSHAG00000011110.1
G3WC30
IRS4
32
iEKPD-Sah-0793
ENSSHAG00000007675.1
G3W0B0
ITGB1BP1
33
iEKPD-Sah-0806
ENSSHAG00000009619.1
G3W6X1
NOS1AP
34
iEKPD-Sah-0782
ENSSHAG00000011576.1
G3WDN8
NUMB
35
iEKPD-Sah-0810
ENSSHAG00000018695.1
G3X334
PID1
36
iEKPD-Sah-0809
ENSSHAG00000008396.1
G3W2P6
RABGAP1
37
iEKPD-Sah-1221
ENSSHAG00000004522.1
G3VPR5
SHC1
38
iEKPD-Sah-1224
ENSSHAG00000011421.1
G3WD51
SHC2
39
iEKPD-Sah-1226
ENSSHAG00000001805.1
G3VFS5
SHC3
40
iEKPD-Sah-1223
ENSSHAG00000015404.1
G3WRT7
SHC4
41
iEKPD-Sah-0800
ENSSHAG00000018900.1
G3X3S5
TBC1D4
42
iEKPD-Sah-1227
ENSSHAG00000017301.1
G3WY93
TNS1
43
iEKPD-Sah-1204
ENSSHAG00000012430.1
G3WGK6
TNS3
44
iEKPD-Sah-1228
ENSSHAG00000011346.1
G3WCW6
TNS4