※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sus-1337	ENSSSCG00000027669.3	I3LPY1
2		iEKPD-Sus-0878	ENSSSCG00000001534.3	F1RZ13	ANKS1A
3		iEKPD-Sus-0877	ENSSSCG00000022083.2	A0A287ABN9	ANKS1B
4		iEKPD-Sus-1327	ENSSSCG00000005250.3	F1SJD2	APBA1
5		iEKPD-Sus-0867	ENSSSCG00000004849.3	F1SNQ5	APBA2
6		iEKPD-Sus-1328	ENSSSCG00000013492.3	A0A287BC13	APBA3
7		iEKPD-Sus-1331	ENSSSCG00000014628.3	F1RMN5	APBB1
8		iEKPD-Sus-1332	ENSSSCG00000022168.2	I3LJX4	APBB2
9		iEKPD-Sus-1336	ENSSSCG00000014366.3	A0A287AG28	APBB3
10		iEKPD-Sus-0874	ENSSSCG00000032357.1	B5LX40	APPL1
11		iEKPD-Sus-0880	ENSSSCG00000000841.3	B6DZ39	appl2; APPL2
12		iEKPD-Sus-0875	ENSSSCG00000003833.3	F1S7A2	DAB1
13		iEKPD-Sus-0876	ENSSSCG00000016857.3	F1SMJ4	DAB2
14		iEKPD-Sus-0885	ENSSSCG00000008265.3	A0A287A4N7	DOK1
15		iEKPD-Sus-0891	ENSSSCG00000009612.3	F1RMC2	DOK2
16		iEKPD-Sus-0895	ENSSSCG00000031653.1	A0A287A5J6	DOK3
17		iEKPD-Sus-0884	ENSSSCG00000029165.2	I3L7P2	DOK4
18		iEKPD-Sus-0881	ENSSSCG00000007488.4	A5GFP8	DOK5; CR956648.1-001
19		iEKPD-Sus-0882	ENSSSCG00000028977.2	A0A287ADY7	DOK6
20		iEKPD-Sus-0879	ENSSSCG00000000600.3	I3LP99	EPS8
21		iEKPD-Sus-0892	ENSSSCG00000026417.2	I3LS55	EPS8L1
22		iEKPD-Sus-0889	ENSSSCG00000012848.3	F1RYY5	EPS8L2
23		iEKPD-Sus-0897	ENSSSCG00000011828.3	F1SFG1	FAM43A
24		iEKPD-Sus-0893	ENSSSCG00000000493.3	A0A287B9N0	FRS2
25		iEKPD-Sus-0894	ENSSSCG00000001624.3	F1RUW8	FRS3
26		iEKPD-Sus-0868	ENSSSCG00000016033.3	F1RYI9	GULP1
27		iEKPD-Sus-0890	ENSSSCG00000025729.2	I3LLF1	IRS1
28		iEKPD-Sus-0888	ENSSSCG00000034763.1	A0A287B726	IRS2
29		iEKPD-Sus-0899	ENSSSCG00000031027.2	C8ZKV5	IRS4
30		iEKPD-Sus-0886	ENSSSCG00000029313.2	A0A286ZTB8	ITGB1BP1
31		iEKPD-Sus-0873	ENSSSCG00000003549.3	F1STU0	LDLRAP1
32		iEKPD-Sus-0896	ENSSSCG00000007665.2	F1RMY3	LOC100515824
33		iEKPD-Sus-0871	ENSSSCG00000013269.3	A0A287AQ99	MAPK8IP1
34		iEKPD-Sus-0872	ENSSSCG00000031660.1	A0A287BRD4	MAPK8IP2
35		iEKPD-Sus-0883	ENSSSCG00000006344.3	A0A287B7A1	NOS1AP
36		iEKPD-Sus-0870	ENSSSCG00000022178.2	A0A287AZZ6	NUMB
37		iEKPD-Sus-0869	ENSSSCG00000023228.2	A0A286ZJP2	NUMBL
38		iEKPD-Sus-0900	ENSSSCG00000035058.1	D3Y4D8	PID1
39		iEKPD-Sus-0901	ENSSSCG00000020743.2	I3LCN0	RABGAP1
40		iEKPD-Sus-1329	ENSSSCG00000008698.3	F1S8N3	RGS12
41		iEKPD-Sus-1339	ENSSSCG00000003509.3	F1SU08	SH2D5
42		iEKPD-Sus-1333	ENSSSCG00000006539.4	F1RGP5	SHC1
43		iEKPD-Sus-1335	ENSSSCG00000040083.1	A0A287BQC2	SHC2
44		iEKPD-Sus-1334	ENSSSCG00000039841.1	A0A287BEY5	SHC3
45		iEKPD-Sus-0887	ENSSSCG00000028983.2	I3LNR0	TBC1D1
46		iEKPD-Sus-0898	ENSSSCG00000009464.3	A0A287AIZ2	TBC1D4
47		iEKPD-Sus-1308	ENSSSCG00000000263.3	F1SFS5	TNS2
48		iEKPD-Sus-1307	ENSSSCG00000016725.3	F1ST78	TNS3
49		iEKPD-Sus-1338	ENSSSCG00000017470.3	F1RXE4	TNS4