※ PTB family introduction

    The phosphotyrosine-binding (PTB) or phosphotyrosine interaction domain (PID) was originally identified in the protein, Shc, as a domain that could bind tyrosine-phosphorylated growth factor receptors. It was the second domain found to bind phosphotyrosine-containing peptides, having been preceded by the discovery of the Src homology 2 (SH2) domain several years earlier. Proteins with this domain are involved in diverse cellular functions, ranging from receptor signaling to protein targeting (1).

Reference
1. Zeng, L. (2014) Structural insights into FRS2 PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 1534-41. PMID: 24470253

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-0914	ENSTGUG00000011219.1	H0ZLV0
2		iEKPD-Tag-0923	ENSTGUG00000008825.1	H0ZET8
3		iEKPD-Tag-0934	ENSTGUG00000004277.1	H0Z1G2
4		iEKPD-Tag-0935	ENSTGUG00000016404.1	H1A1E4
5		iEKPD-Tag-0938	ENSTGUG00000000412.1	H0YQ66
6		iEKPD-Tag-0940	ENSTGUG00000002107.1	H0YV51
7		iEKPD-Tag-0924	ENSTGUG00000001756.1	H0YU51	ANKS1A
8		iEKPD-Tag-1330	ENSTGUG00000001066.1	H0YS41	APBA1
9		iEKPD-Tag-1331	ENSTGUG00000005613.1	H0Z5F2	APBA2
10		iEKPD-Tag-1329	ENSTGUG00000000142.1	H0YPE8	APBA3
11		iEKPD-Tag-1336	ENSTGUG00000008675.1	H0ZED9	APBB2
12		iEKPD-Tag-1340	ENSTGUG00000001677.1	H0YTX1	APBB3
13		iEKPD-Tag-0918	ENSTGUG00000007194.1	H0ZA25	APPL1
14		iEKPD-Tag-0929	ENSTGUG00000011070.1	H0ZLE9	APPL2
15		iEKPD-Tag-0919	ENSTGUG00000009639.1	H0ZH85	DAB1
16		iEKPD-Tag-0920	ENSTGUG00000002156.1	H0YVB3	DAB2
17		iEKPD-Tag-0928	ENSTGUG00000004974.1	H0Z3J0	DOK4
18		iEKPD-Tag-0926	ENSTGUG00000009250.1	H0ZG33	DOK6
19		iEKPD-Tag-0925	ENSTGUG00000012399.1	H0ZQ83	EPS8
20		iEKPD-Tag-0931	ENSTGUG00000007213.1	H0ZA30	EPS8L2
21		iEKPD-Tag-0943	ENSTGUG00000009067.1	H0ZFH5	FAM43A
22		iEKPD-Tag-0937	ENSTGUG00000006906.1	H0Z952	FRS2
23		iEKPD-Tag-0939	ENSTGUG00000017438.1	H1A4A4	FRS3
24		iEKPD-Tag-0913	ENSTGUG00000011065.1	H0ZLD8	GULP1
25		iEKPD-Tag-0932	ENSTGUG00000008136.1	H0ZCS2	IRS1
26		iEKPD-Tag-0927	ENSTGUG00000013015.1	H0ZS06	ITGB1BP1
27		iEKPD-Tag-0916	ENSTGUG00000001098.1	H0YS72	LDLRAP1
28		iEKPD-Tag-0922	ENSTGUG00000014679.1	H0ZWP4	LOC100231911
29		iEKPD-Tag-0915	ENSTGUG00000010712.1	H0ZKC5	MAPK8IP1
30		iEKPD-Tag-0917	ENSTGUG00000015603.1	H0ZZ85	MAPK8IP2
31		iEKPD-Tag-0933	ENSTGUG00000017160.1	H1A3I2	NOS1AP
32		iEKPD-Tag-0942	ENSTGUG00000008301.1	H0ZD94	PID1
33		iEKPD-Tag-0941	ENSTGUG00000006934.1	H0Z9C8	RABGAP1
34		iEKPD-Tag-1332	ENSTGUG00000010365.1	H0ZJF0	RGS12
35		iEKPD-Tag-1338	ENSTGUG00000004152.1	H0Z180	SHC1
36		iEKPD-Tag-0921	ENSTGUG00000000601.1	H0YQQ5	SHC2
37		iEKPD-Tag-1337	ENSTGUG00000000448.1	H0YQB5	SHC3
38		iEKPD-Tag-1339	ENSTGUG00000007228.1	H0ZA57	SHC4
39		iEKPD-Tag-0930	ENSTGUG00000009056.1	H0ZFL7	TBC1D1
40		iEKPD-Tag-0936	ENSTGUG00000012530.1	H0ZQK9	TBC1D4
41		iEKPD-Tag-1315	ENSTGUG00000005126.1	H0Z413	TNS1
42		iEKPD-Tag-1314	ENSTGUG00000007104.1	H0Z9T5	TNS3
43		iEKPD-Tag-1341	ENSTGUG00000002351.1	H0YVU8	TNS4