※ SH2 family introduction

    The SH2 (Src Homology 2) domain is a structurally conserved protein domain contained within the Src and in many other intracellular signal-transducing proteins. SH2 domains allow proteins containing those domains to dock to phosphorylated tyrosine residues on other proteins. SH2 domains are commonly found in adapter proteins that aid in the signal transduction of receptor tyrosine kinase pathways. The yeast genome encodes only one SH2 domain-containing protein, the transcription factor Spt6. Recent study demonstrated that the Spt6 SH2 domain region can binds to Ser-phosphorylated CTD (1).

Reference
1. Kaneko, T. (2012) Phosphotyrosine recognition domains: the typical, the atypical and the versatile. Cell Commun Signal, 10, 32. PMID: 23134684

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-0946	ENSTGUG00000000392.1	H0YQ56
2		iEKPD-Tag-0947	ENSTGUG00000008122.1	H0ZCU7
3		iEKPD-Tag-0948	ENSTGUG00000012748.1	H0ZR85
4		iEKPD-Tag-0949	ENSTGUG00000010180.1	H0ZIT0
5		iEKPD-Tag-0952	ENSTGUG00000015218.1	H0ZY59
6		iEKPD-Tag-0956	ENSTGUG00000004965.1	H0Z3H2
7		iEKPD-Tag-0957	ENSTGUG00000010177.1	H0ZIU5
8		iEKPD-Tag-0958	ENSTGUG00000000091.1	H0YP98
9		iEKPD-Tag-1306	ENSTGUG00000015142.1	H0ZY02
10		iEKPD-Tag-0968	ENSTGUG00000013605.1	H0ZTR2
11		iEKPD-Tag-0973	ENSTGUG00000007041.1	H0Z9J8
12		iEKPD-Tag-0974	ENSTGUG00000009062.1	H0ZFH2
13		iEKPD-Tag-0983	ENSTGUG00000004373.1	H0Z1Q6
14		iEKPD-Tag-0989	ENSTGUG00000009664.1	H0ZH95
15		iEKPD-Tag-0994	ENSTGUG00000014316.1	H0ZVR7
16		iEKPD-Tag-0997	ENSTGUG00000014969.1	H0ZXG7
17		iEKPD-Tag-0998	ENSTGUG00000018336.1	H1A4S9
18		iEKPD-Tag-0999	ENSTGUG00000016324.1	H1A167
19		iEKPD-Tag-1000	ENSTGUG00000018177.1	H1A5N3
20		iEKPD-Tag-1001	ENSTGUG00000015941.1	H1A051
21		iEKPD-Tag-1002	ENSTGUG00000013939.1	H0ZUP7
22		iEKPD-Tag-1003	ENSTGUG00000001884.1	H0YUH1
23		iEKPD-Tag-1004	ENSTGUG00000014700.1	H0ZWR0
24		iEKPD-Tag-1005	ENSTGUG00000015304.1	H0ZYE2
25		iEKPD-Tag-1006	ENSTGUG00000007391.1	H0ZAK2
26		iEKPD-Tag-1007	ENSTGUG00000017467.1	H1A4D6
27		iEKPD-Tag-1010	ENSTGUG00000015493.1	H0ZYX6
28		iEKPD-Tag-1011	ENSTGUG00000013762.1	H0ZU65
29		iEKPD-Tag-1013	ENSTGUG00000016575.1	H1A1W1
30		iEKPD-Tag-1014	ENSTGUG00000016640.1	H1A222
31		iEKPD-Tag-1015	ENSTGUG00000018140.1	H1A5Q7
32		iEKPD-Tag-1284	ENSTGUG00000004720.1	H0Z2V6	ABL1
33		iEKPD-Tag-1308	ENSTGUG00000017391.1	H1A456	ABL2
34		iEKPD-Tag-0980	ENSTGUG00000005886.1	H0Z659	BCAR3
35		iEKPD-Tag-1304	ENSTGUG00000013299.1	H0ZSU8	BLK
36		iEKPD-Tag-1320	ENSTGUG00000000375.1	H0YQ30	CBL
37		iEKPD-Tag-1321	ENSTGUG00000013612.1	H0ZTR9	CBLB
38		iEKPD-Tag-0979	ENSTGUG00000008848.1	H0ZEX4	CHN1
39		iEKPD-Tag-0972	ENSTGUG00000004724.1	H0Z2R4	CISH
40		iEKPD-Tag-0950	ENSTGUG00000005424.1	H0Z4T7	CRK
41		iEKPD-Tag-0961	ENSTGUG00000003467.1	H0YZ45	DAPP1
42		iEKPD-Tag-1279	ENSTGUG00000000963.1	H0YRT1	FER
43		iEKPD-Tag-1297	ENSTGUG00000010113.1	H0ZIM7	FES
44		iEKPD-Tag-1278	ENSTGUG00000000957.1	H0YRS7	FGR
45		iEKPD-Tag-1301	ENSTGUG00000011957.1	H0ZNZ2	FRK
46		iEKPD-Tag-1302	ENSTGUG00000011998.1	H0ZP43	FYN
47		iEKPD-Tag-0960	ENSTGUG00000007941.1	H0ZCA3	GRB10
48		iEKPD-Tag-0959	ENSTGUG00000006979.1	H0Z9G6	GRB14
49		iEKPD-Tag-0951	ENSTGUG00000008612.1	B5FZR7	GRB2
50		iEKPD-Tag-1289	ENSTGUG00000006558.1	H0Z868	HCK
51		iEKPD-Tag-0962	ENSTGUG00000007342.1	H0ZAK0	INPP5D
52		iEKPD-Tag-0986	ENSTGUG00000002648.1	H0YWR4	INPPL1
53		iEKPD-Tag-1277	ENSTGUG00000000655.1	H0YQX2	ITK
54		iEKPD-Tag-1296	ENSTGUG00000009979.1	H0ZIA6	JAK1
55		iEKPD-Tag-1286	ENSTGUG00000005043.1	H0Z3Y5	JAK2
56		iEKPD-Tag-0966	ENSTGUG00000001570.1	H0YTK6	LCP2
57		iEKPD-Tag-1009	ENSTGUG00000002572.1	H0YWJ7	LOC100222731
58		iEKPD-Tag-0981	ENSTGUG00000015389.1	H0ZYN6	LOC100229574
59		iEKPD-Tag-1305	ENSTGUG00000013782.1	H0ZUA2	LOC100230194
60		iEKPD-Tag-1012	ENSTGUG00000015210.1	H0ZY54	LOC105759979
61		iEKPD-Tag-1008	ENSTGUG00000018156.1	H1A5I5	LOC105760232
62		iEKPD-Tag-1307	ENSTGUG00000015619.1	H0ZZB8	LOC105760431
63		iEKPD-Tag-1300	ENSTGUG00000011056.1	H0ZLG0	LYN
64		iEKPD-Tag-1272	ENSTGUG00000000123.1	H0YPD9	MATK
65		iEKPD-Tag-0954	ENSTGUG00000009731.1	H0ZHH1	NCK2
66		iEKPD-Tag-0944	ENSTGUG00000002982.1	H0YXT8	PIK3R1
67		iEKPD-Tag-0945	ENSTGUG00000004737.1	H0Z304	PLCG1
68		iEKPD-Tag-1319	ENSTGUG00000004405.1	H0Z1Z9	PLCG2
69		iEKPD-Tag-1312	ENSTGUG00000006795.1	H0Z8W9	PTPN11
70		iEKPD-Tag-1311	ENSTGUG00000013276.1	H0ZSS4	PTPN6
71		iEKPD-Tag-1335	ENSTGUG00000001169.1	H0YSF7	RASA1
72		iEKPD-Tag-0990	ENSTGUG00000007689.1	H0ZBH6	RIN2
73		iEKPD-Tag-0995	ENSTGUG00000012587.1	H0ZQR5	RIN3
74		iEKPD-Tag-0969	ENSTGUG00000004439.1	H0Z1Y1	SH2B2
75		iEKPD-Tag-0992	ENSTGUG00000006491.1	H0Z7W7	SH2B3
76		iEKPD-Tag-0970	ENSTGUG00000003791.1	H0Z018	SH2D1A
77		iEKPD-Tag-0987	ENSTGUG00000016819.1	H1A2J7	SH2D2A
78		iEKPD-Tag-0976	ENSTGUG00000003600.1	H0YZJ7	SH2D3C
79		iEKPD-Tag-0978	ENSTGUG00000006102.1	H0Z6R9	SH2D4B
80		iEKPD-Tag-0988	ENSTGUG00000010489.1	H0ZJR1	SH3BP2
81		iEKPD-Tag-1338	ENSTGUG00000004152.1	H0Z180	SHC1
82		iEKPD-Tag-1337	ENSTGUG00000000448.1	H0YQB5	SHC3
83		iEKPD-Tag-1339	ENSTGUG00000007228.1	H0ZA57	SHC4
84		iEKPD-Tag-0984	ENSTGUG00000004055.1	H0Z0U2	SHE
85		iEKPD-Tag-0955	ENSTGUG00000012567.1	H0ZQQ0	SLA
86		iEKPD-Tag-0975	ENSTGUG00000004867.1	H0Z361	SOCS1
87		iEKPD-Tag-0964	ENSTGUG00000008281.1	H0ZD66	SOCS2
88		iEKPD-Tag-0982	ENSTGUG00000003345.1	H0YYR7	SOCS3
89		iEKPD-Tag-0985	ENSTGUG00000013079.1	H0ZS71	SOCS4
90		iEKPD-Tag-0977	ENSTGUG00000002631.1	H0YWM9	SOCS5
91		iEKPD-Tag-0963	ENSTGUG00000009217.1	H0ZFY4	SOCS6
92		iEKPD-Tag-0953	ENSTGUG00000003337.1	H0YYQ7	SOCS7
93		iEKPD-Tag-1285	ENSTGUG00000004937.1	H0Z3F7	SRC
94		iEKPD-Tag-1290	ENSTGUG00000007405.1	H0ZAM6	SRMS
95		iEKPD-Tag-0971	ENSTGUG00000010768.1	H0ZKL5	STAT1
96		iEKPD-Tag-0991	ENSTGUG00000002600.1	H0YWQ5	STAT3
97		iEKPD-Tag-0996	ENSTGUG00000015716.1	H0ZZL2	STAT6
98		iEKPD-Tag-0993	ENSTGUG00000006101.1	H0Z6V3	SUPT6H
99		iEKPD-Tag-1276	ENSTGUG00000000422.1	H0YQ82	SYK
100		iEKPD-Tag-1294	ENSTGUG00000008092.1	H0ZCS7	TEC
101		iEKPD-Tag-1315	ENSTGUG00000005126.1	H0Z413	TNS1
102		iEKPD-Tag-1314	ENSTGUG00000007104.1	H0Z9T5	TNS3
103		iEKPD-Tag-1341	ENSTGUG00000002351.1	H0YVU8	TNS4
104		iEKPD-Tag-0965	ENSTGUG00000005682.1	H0Z5P6	VAV2
105		iEKPD-Tag-0967	ENSTGUG00000004635.1	H0Z2W1	VAV3
106		iEKPD-Tag-1298	ENSTGUG00000010159.1	H0ZIS1	YES1
107		iEKPD-Tag-1274	ENSTGUG00000000330.1	H0YPY8	ZAP70