PPBDs-containing Proteins Classification: (pS/pT)/LRR※ LRR family introduction LRRs occur in proteins ranging from viruses to eukaryotes, and appear to provide a structural framework for the formation of protein-protein interactions. Grr1 LRR is critical for the recognition of phosphorylated targets of SCF (1).
Reference
1. Hsiung YG, Chang HC, Pellequer JL, La Valle R, Lanker S, Wittenberg C. (2001) F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat. Mol Cell Biol, 21(7), 2506-20. PMID: 11259599
p(S/T) LRR in eukaryotes:
1. Hsiung YG, Chang HC, Pellequer JL, La Valle R, Lanker S, Wittenberg C. (2001) F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat. Mol Cell Biol, 21(7), 2506-20. PMID: 11259599
p(S/T) LRR in eukaryotes: