PPBDs-containing Proteins Classification: pY/CBL_PTB※ CBL_PTB family introduction Cbl-PTB is composed of three interacting domains: a four-helix bundle (4H), an EF-hand calcium-binding domain, and a divergent SH2 domain. The calcium-bound EF-hand wedges between the 4H and SH2 domains, and roughly determines their relative orientation. The three domains together form an integrated phosphoprotein-recognition module (1).
Reference
1. https://prosite.expasy.org/rule/PRU00839
pY CBL_PTB in eukaryotes:
1. https://prosite.expasy.org/rule/PRU00839
pY CBL_PTB in eukaryotes: